Identification | More | [Name]
2,3,5-Triphenyltetrazolium chloride | [CAS]
298-96-4 | [Synonyms]
2,3,5-TRIPHENYL-2H-TETRAZOLIUM CHLORIDE 2,3,5-TRIPHENYLTETRAZOLIUM CHLORIDE 2,5-dihydro-6-hydroxy-2-methyl-3-mercapto-5-oxo-1,2,3-triazine 2,5-Dihydro-6-hydroxy-2-methyl-3-mercapto-5-oxo-1,2,4-triazione 2,5-DIHYDRO-6-HYDROXY-3-MERCAPTO-2-METHYL-5-OXO-1,2,4-TRIAZINE 2H-TETRAZOLIUM, 2,3,5-TRIPHENYL-, CHLORIDE 2-MERCAPTO-3-METHYL-5-OXO-6-HYDROXY-1,2,4-TRIAZINE 2-METHYL-3-THIOXOHEXAHYDRO-1,2,4-TRIAZINE-5,6-DIONE LABOTEST-BB LT00086927 RARECHEM AH BS 0067 TCC TETRAHYDRO-2-METHYL-3-THIOXO-1,2,4-TRIAZINE-5,6-DIONE TETRAZOLE RED TETRAZOLIUM CHLORIDE TETRAZOLIUM RED TETRAZOLIUM RED CHLORIDE TETRAZOLIUM SALT THIOTRIAZINONE TRIPHENYLTETRAZOLIUM CHLORIDE TTC | [EINECS(EC#)]
206-071-6 | [Molecular Formula]
C19H15ClN4 | [MDL Number]
MFCD00011963 | [Molecular Weight]
334.8 | [MOL File]
298-96-4.mol |
Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
250 °C(lit.)
| [Boiling point ]
490.96°C (rough estimate) | [density ]
1.1704 (rough estimate) | [refractive index ]
1.6110 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
H2O: may be clear to slightly hazy
| [form ]
powder | [color ]
faint yellow
| [Stability:]
Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents. | [Water Solubility ]
Soluble in water, ethanol and acetone. Insoluble in ether. | [Sensitive ]
Light Sensitive & Hygroscopic | [λmax]
247 nm | [Merck ]
14,9744 | [BRN ]
3923356 | [Biological Applications]
Algae viability assay; microbial growth assays; transketolase activity screening assays; detecting bacteria,g-hydroxybutyric acid (GHB),microorganisms,myocardial infarction; measuring dehydrogenase activity; treating cancer | [InChIKey]
PKDBCJSWQUOKDO-UHFFFAOYSA-M | [CAS DataBase Reference]
298-96-4(CAS DataBase Reference) | [EPA Substance Registry System]
298-96-4(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
XF8100000
| [F ]
3-8-10 | [TSCA ]
Yes | [HS Code ]
29339900 | [Toxicity]
LD50 intravenous in mouse: 5600ug/kg |
Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies. | [Uses]
2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia
| [Uses]
In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases. | [Definition]
ChEBI: An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. | [General Description]
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke. | [Purification Methods]
Crystallise TTZ from EtOH or CHCl3, and dry it at 105o. [Beilstein 26 H 363, 26 II 216, 26 III/IV 1774.] |
Spectrum Detail | Back Directory | [Spectrum Detail]
2,3,5-Triphenyltetrazolium chloride(298-96-4)1HNMR 2,3,5-Triphenyltetrazolium chloride(298-96-4)13CNMR 2,3,5-Triphenyltetrazolium chloride(298-96-4)IR1 2,3,5-Triphenyltetrazolium chloride(298-96-4)IR2 2,3,5-Triphenyltetrazolium chloride(298-96-4)Raman
|
|
|