Identification | Back Directory | [Name]
APIGENIN-7-GLUCURONIDE | [CAS]
29741-09-1 | [Synonyms]
Scutellarin A Glucuronyl-7-apigenin APIGENIN-7-GLUCURONIDE APIGENIN-7-O-GLUCURONIDE Apigenin 7-O-b-glucuronide Apigenin 7-beta-glucuronide Apigenin 7-O-β-D-glucuronide Apigenin 7-O-beta-glucuronide Apigenin 7-O-beta-D-glucuronide APIGENIN-7-GLUCURONIDE USP/EP/BP Apigenin-7-O-beta-D glucuronoside 5,4'-Dihydroxy-7-(β-D-glucopyranuronosyloxy)flavone Apigenin 7-glucuronide(Apigenin-7-O-β-D-glucuronide) 4',5-Dihydroxy-7-[(β-D-glucopyranuronosyl)oxy]flavone 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl beta-D-Glucuronide 7-(6-Oxo-β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one β-D-Glucopyranosiduronic acid, 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid (3S,4S,5S,6S)-3,4,5-Trihydroxy-6-(5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)-tetrahydro-2H-pyran-2-carboxylic acid | [Molecular Formula]
C21H18O11 | [MDL Number]
MFCD00800694 | [MOL File]
29741-09-1.mol | [Molecular Weight]
446.36 |
Chemical Properties | Back Directory | [Melting point ]
>300℃ | [Boiling point ]
841.8±65.0 °C(Predicted) | [density ]
1.737 | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMSO : 65 mg/mL (145.62 mM; Need ultrasonic) | [form ]
powder | [pka]
2.73±0.70(Predicted) | [color ]
Yellowish | [InChIKey]
JBFOLLJCGUCDQP-ZFORQUDYSA-N |
Hazard Information | Back Directory | [Uses]
Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells. | [Definition]
ChEBI: Apigenin 7-glucuronide is a member of flavonoids and a glucosiduronic acid. | [target]
NO | PGE | TNF-α | NOS | COX | AP-1 | ERK | p38MAPK | MMP-3 | MMP-8 | MMP-9 | MMP-13 |
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