| Identification | Back Directory | [Name]
PONCIRIN | [CAS]
14941-08-3 | [Synonyms]
C09830
PONCIRIN
(2S)-Poncirin
Citrifolioside
Einecs 239-020-1
PONCIRIN WITH HPLC
PONCIRIN USP/EP/BP
4'-O-Methylnaringin
ISOSAKURANETIN-7-NEOHESPERIDOSIDE
Neohesperidoside isosakuranetin-7
ISOSAKURANETIN-7-O-NEOHESPERIDOSID
ISOSAKURANETIN-7-O-NEOHESPERIDOSIDE
ISOSAKURANETIN-7-NEOHESPERIDOSIDE hplc
Poncirin, froM Poncirus trifoliata (L.) Raf.
Poncirin, 98%, from Poncirus trifoliata (L.) Raf.
5,7-Dihydroxy-4'-methoxyflavanone 7-neohesperidoside
Poncirin
5,7-Dihydroxy-4'-methoxyflavanone 7-neohesperidoside
(2S)-4'-Methoxy-5-hydroxy-7-(2-O-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)flavanone
(s)-5,7-dihydroxy-4'-methoxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]
(S)-5,7-DIHYDROXY-4'-METHOXYFLAVANONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
Isosakuranetin-7-neohesperidoside, (S)-5,7-Dihydroxy-4μ-methoxyflavanone-7-[2-O-(α-L-rhamnopyranosyl)-β-D-glucopyranoside]
(S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
(S)-7-((2-o-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-, (2S)- | [EINECS(EC#)]
239-020-1 | [Molecular Formula]
C28H34O14 | [MDL Number]
MFCD00017476 | [MOL File]
14941-08-3.mol | [Molecular Weight]
594.56 |
| Chemical Properties | Back Directory | [Melting point ]
210°C | [Boiling point ]
900.1±65.0 °C(Predicted) | [density ]
1.59 | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in methan | [form ]
neat | [pka]
7.15±0.40(Predicted) | [color ]
Yellow | [BRN ]
74301 | [InChIKey]
NLAWPKPYBMEWIR-QMIPVYQNSA-N | [LogP]
3.390 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white powder | [Uses]
Poncirin is a natural bitter flavanone glycoside present in many species of citrus fruits which has various biological benefits such as antioxidant, antimicrobial, anti-inflammatory and anti-cancer activities. Main constituent used in traditional Chinese medicine for inflammation, asthma, and infection diseases. | [Definition]
ChEBI: (2S)-poncirin is a flavanone glycoside that is 4'-methoxy-5,7-dihydroxyflavanone attached to a neohesperidose (alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranose) residue via a glycosidic linkage. It has been isolated from the fruits of Poncirus trifoliata and exhibits inhibitory activity against liopolysaccharide (LPS)-induced prostaglandin E2 and interleukin-6 (IL-6) production. It has a role as a plant metabolite. It is a monomethoxyflavanone, a flavanone glycoside, a disaccharide derivative, a neohesperidoside and a member of 4'-methoxyflavanones. It is functionally related to a 4'-methoxy-5,7-dihydroxyflavanone. | [in vivo]
Poncirin (intraperitoneal administration; 30 mg/kg) markedly reduces the pain behavior in both acetic acid-induced visceral pain and formalin-induced tonic pain models inComplete Freund’s Adjuvant (CFA)-induced inflammatory pain model[1]. |
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