| Identification | Back Directory | [Name]
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide | [CAS]
289472-80-6 | [Synonyms]
Bortezomib IMP
BortezoMib IMpurity
Bortezomib Impuirty 41
Bortezomib Impurity 41
Bortezomib USP Impurity B
Bortezomib Amide Impurity
Bortezomib Related compaund B
Bortezomib USP Related Compoud B
Bortezomib impurity 6/Bortezomib Amide Impurity
Bortezomib Related Compund B/ Bortezomib Amide Analog
N-[(1S)-2-Amino-1-benzyl-2-oxoethyl]pyrazine-2-carboxamide
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
(S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
2-PyrazinecarboxaMide, N-[(1S)-2-aMino-2-oxo-1-(phenylMethyl)ethyl]-
N-((R)-1-(((S)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3- phenylpropan-2-yl)pyrazine-2-carboxamide | [Molecular Formula]
C14H14N4O2 | [MDL Number]
MFCD26743605 | [MOL File]
289472-80-6.mol | [Molecular Weight]
270.29 |
| Chemical Properties | Back Directory | [Melting point ]
168-170°C | [Boiling point ]
619.4±55.0 °C(Predicted) | [density ]
1.280±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
11.92±0.46(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the
ubiquitin-proteasome pathway. |
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