| Identification | Back Directory | [Name]
CCG-1423 | [CAS]
285986-88-1 | [Synonyms]
CCg
CS-1769
CCG-1423
CCG1423, >98%
CCG 1423;CCG-1423
CCG-1423 USP/EP/BP
Rho/SRF Pathway Inhibitor, CCG-1423
Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide
N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide
N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide
N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide
Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-
N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423 | [Molecular Formula]
C18H13ClF6N2O3 | [MDL Number]
MFCD01566719 | [MOL File]
285986-88-1.mol | [Molecular Weight]
454.751 |
| Hazard Information | Back Directory | [Uses]
Cell permeable inhibitor of RhoA- and RhoC-mediated signaling. Inhibits LPA-induced DNA synthesis in PC-3 prostate cancer cell lines (<1μM) and inhibits the growth of RhoC-overexpressing melanoma cell lines (A375M2 and SK-Mel-147) at nanomolar concentrations. | [Biological Activity]
CCG-1423 is a potent and specific inhibitor of Rho pathway signaling and activation of serum response factor (SRF) transcription. CCG-1423 inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13. Also CCG-1423 selectively inhibits DNA synthesisproliferation and invasion of Rho-overexpressing cell lines. | [storage]
+4°C |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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