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ChemicalBook--->CAS DataBase List--->284028-90-6

284028-90-6

284028-90-6 Structure

284028-90-6 Structure
IdentificationBack Directory
[Name]

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
[CAS]

284028-90-6
[Synonyms]

DR 2313
IR 2313
SC-202756
DR2313 >=98% (HPLC)
PARP Inhibitor XI, DR2313
4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2
7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one
4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL-
3,5,7,8-tetrahydro-2-methyl-4h-thiopyrano(4,3-d)pyrimidin-4-one, 98%(HPLC)
[EINECS(EC#)]

200-589-5
[Molecular Formula]

C8H10N2OS
[MDL Number]

MFCD08703132
[MOL File]

284028-90-6.mol
[Molecular Weight]

182.24
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

H2O: >2mg/mL (warmed)
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC 50 values are 0.20 and 0.24 μ M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro . Brain penetrant.
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