Identification | Back Directory | [Name]
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE | [CAS]
284028-90-6 | [Synonyms]
DR 2313 IR 2313 SC-202756 DR2313 >=98% (HPLC) PARP Inhibitor XI, DR2313 4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2 7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE 2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one 4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL- 3,5,7,8-tetrahydro-2-methyl-4h-thiopyrano(4,3-d)pyrimidin-4-one, 98%(HPLC) | [EINECS(EC#)]
200-589-5 | [Molecular Formula]
C8H10N2OS | [MDL Number]
MFCD08703132 | [MOL File]
284028-90-6.mol | [Molecular Weight]
182.24 |
Hazard Information | Back Directory | [Biological Activity]
Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC 50 values are 0.20 and 0.24 μ M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro . Brain penetrant. |
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Company Name: |
China Langchem Inc.
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0086-21-58956006 |
Website: |
m.is0513.com/ShowSupplierProductsList19141/0.htm |
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