Identification | Back Directory | [Name]
(S)-(+)-1-Methoxy-2-propanol | [CAS]
26550-55-0 | [Synonyms]
(S)-1-methoxypropanol (S)-1-METHOXY-2-PROPANOL (S)-1-Methoxypropan-2-ol (S)-(+)-1-METHOXY-2-PROPANOL (S)-2-HYDROXY-1-METHOXYPROPANE (S)-(+)-1-METHOXY-2-PROPANOL 98% (S)-(+)-1-Methoxy-2-propanol,99% (S)-(+)-1-Methoxy-2-propanol (S)-(+)-1-Methoxy-2-propanol, 99% 1ML (S)-(+)-1-Methoxy-2-propanol, 99% 5ML (S)-(+)-PROPYLENE GLYCOL 1-METHYL ETHER (S)-(+)-1-Methoxy-2-propanol >=98.5% (sum of enantiomers) | [Molecular Formula]
C4H10O2 | [MDL Number]
MFCD01632588 | [MOL File]
26550-55-0.mol | [Molecular Weight]
90.12 |
Chemical Properties | Back Directory | [Appearance]
Colorless to light yellow liqui | [Melting point ]
-84.2°C (estimate) | [alpha ]
20 º (c=10, CHCl3) | [Boiling point ]
118-119 °C
| [density ]
0.921 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.403
| [Fp ]
33 °C
| [storage temp. ]
Flammables area | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Liquid | [pka]
14.49±0.20(Predicted) | [color ]
Clear colorless | [optical activity]
[α]20/D +22±2°, c = 10% in chloroform | [BRN ]
1718940 | [Stability:]
Volatile | [InChIKey]
ARXJGSRGQADJSQ-BYPYZUCNSA-N | [CAS DataBase Reference]
26550-55-0 |
Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liqui | [Uses]
(S)-(+)-1-Methoxy-2-propanol can be used as a reactant to prepare:
- (S)-1-methoxypropan-2-yl 4-methylbenzenesulfonate by reacting with tosyl chloride in the presence of pyridine.
- Thiazolopyridine urea derivatives.
- Quinazoline derivatives as potential inhibitors of EGFR/HER-2 tyrosine kinases.
| [Purification Methods]
Wash the ethers with aqueous NaHCO3 in the presence of solid NaCl, dry them with MgSO4 and fractionally distil them. The RS-acetate [108-65-6] M 132.2 has b 145-146o/atm. The R(+) and S(-) enantiomers have [] D ±20.5o (c 10, H2O). [Beilstein 1 II 536, 1 III 2146, 1 IV 2471.] |
|
|