| Identification | More | [Name]
2-AMINO-9H-PYRIDO[2,3-B]INDOLE | [CAS]
26148-68-5 | [Synonyms]
2-AMINO-9H-PYRIDO[2,3-B]INDOLE
AC
1h-pyrido(2,3-b)indol-2-amine
2-amino-alpha-carboline
3-b)indole,2-amino-9h-pyrido(
amino-alpha-carboline
2-AMINO-9H-PYRIDOL[2,3-BETA]INDOLE
2-AMINO-9H-PYRIDOL(2,3-B)INDOLE
AAC
PYRIDO(2,3-B)INDOLE,2-AMINO-
2-AMINO-PYRIDO(2,3-B)INDOLE
AALPHAC
A-ALPHA-C(2-AMINO-9H-PYRIDO[2,3-B]INDOLE
2-AMINO-9H-PYRIDO(2,3)INDOLE
1H-Pyrido[2,3-β]indol-2-amine
2-Amino-α-carboline
9H-1,9-Diazafluoren-2-amine
A-Alpha-C(2-amino-9H-pyrdio[2,3-B]Indole)
2-Amino-a-carboline
9H-Pyrido[2,3-b]indol-2-amine | [Molecular Formula]
C11H9N3 | [MDL Number]
MFCD00210750 | [Molecular Weight]
183.21 | [MOL File]
26148-68-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
194-196 | [Boiling point ]
306.89°C (rough estimate) | [density ]
1.2078 (rough estimate) | [refractive index ]
1.6500 (estimate) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Methanol (Slightly) | [form ]
Solid | [pka]
14.87±0.40(Predicted) | [color ]
Beige to Light Orange | [Usage]
A pyrolysate that exhibited mutagenic activity toward Salmonella typhimurium TA98 and TA100 from the pyrolytic products of soybean globulin | [InChI]
InChI=1S/C11H9N3/c12-10-6-5-8-7-3-1-2-4-9(7)13-11(8)14-10/h1-6H,(H3,12,13,14) | [InChIKey]
FJTNLJLPLJDTRM-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=CC=C2)C2=CC=C(N)N=C12 | [CAS DataBase Reference]
26148-68-5(CAS DataBase Reference) | [IARC]
2B (Vol. 40, Sup 7) 1987 | [EPA Substance Registry System]
2-Amino-9H-pyrido[2,3-b]indole (26148-68-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [RIDADR ]
2811 | [Hazard Note ]
Irritant/Mutagen | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
2933998090 | [Safety Profile]
Suspected carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx,. | [Hazardous Substances Data]
26148-68-5(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
A pyrolysate that exhibited mutagenic activity toward Salmonella typhimurium TA98 and TA100 from the pyrolytic products of soybean globulin. 2-Amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-3-methyl-9
H-pyrido[2,3-b]indole (MeAαC) are two mutagenic and carcinogenic heterocyclic amines formed during ordinary cooking. | [Definition]
ChEBI: 2-Amino-9H-pyrido[2,3-b]indole is a pyridoindole. | [Biological Activity]
AαC (2-Amino-9H-pyrido[2-3-b]indole) is a potential human carcinogenwhich is generated by the combustion of tobaccoor by pyrolysis of protein. AαC potentially contributes to liver or digestive tract cancers. Inside body AαC is metabolized to intermediates (possibly short-lived nitrenium ion of AαC) th at react with DNA. |
|
|