| Identification | More | [Name]
Ethyl picolinate | [CAS]
2524-52-9 | [Synonyms]
2-PICOLINIC ACID, ETHYL ESTER
2-PYRIDINECARBOXYLIC ACID ETHYL ESTER
ETHYL 2-PICOLINATE
ETHYL 2-PYRIDINECARBOXYLATE
ETHYL PICOLINATE
ETHYL PYRIDINE-2-CARBOXYLATE
PICOLINIC ACID ETHYL ESTER
PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
RARECHEM AL BI 0182
2-(Ethoxycarbonyl)pyridine
Ethyl pyridine-2-carboxylate~Picolinic acid ethyl ester
2-Pyridinecarboxylicacid,ethylester(9CI)
2-ETHYL PICOLINATE
Ethyl picolinate ,99% | [EINECS(EC#)]
219-758-0 | [Molecular Formula]
C8H9NO2 | [MDL Number]
MFCD00006292 | [Molecular Weight]
151.16 | [MOL File]
2524-52-9.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellowish or pink liquid | [Melting point ]
2 °C (lit.) | [Boiling point ]
240-241 °C (lit.) | [density ]
1.119 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.511(lit.)
| [Fp ]
225 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Liquid | [pka]
1.83±0.10(Predicted) | [color ]
Clear yellow or pink | [Water Solubility ]
miscible | [Detection Methods]
GC,NMR,HPLC | [BRN ]
122485 | [InChIKey]
FQYYIPZPELSLDK-UHFFFAOYSA-N | [LogP]
0.870 | [CAS DataBase Reference]
2524-52-9(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Pyridinecarboxylic acid, ethyl ester(2524-52-9) | [EPA Substance Registry System]
2524-52-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellowish or pink liquid | [Uses]
Ethyl picolinate can be used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.
| [Uses]
Ethyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 43, p. 1028, 1995 DOI: 10.1248/cpb.43.1028 |
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