| Identification | Back Directory | [Name]
JTC 801 | [CAS]
244218-51-7 | [Synonyms]
CS-161
JTC 801
JTC 801 HCl
JTC-801/JTC801
JTC 801 USP/EP/BP
JTC-801 >=98% (HPLC)
JTC-801 hydrochloride
N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamidehydrochloride
N-(4-AMino-2-Methyl-quinolin-6-yl)-2-(4-ethyl-phenoxyMethyl)-benzaMide hydrochloride
Benzamide,N-(4-amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]-, hydrochloride
N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamide monohydrochloride | [Molecular Formula]
C26H25N3O2.ClH | [MDL Number]
MFCD06198707 | [MOL File]
244218-51-7.mol | [Molecular Weight]
447.963 |
| Chemical Properties | Back Directory | [Melting point ]
235℃ | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO: ≥20mg/mL | [form ]
powder | [color ]
tan | [InChIKey]
NQLIYKXNAXKMBL-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Uses]
JTC 801 is a novel opioid receptor-like1 (ORL1) receptor antagonist. | [Biological Activity]
High affinity, selective NOP receptor antagonist (K i = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human μ -, κ - and δ -opioid receptors respectively. In vivo shows anti-nociceptive effects in acute pain models. Orally active. | [storage]
Desiccate at RT |
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