| Identification | Back Directory | [Name]
Thalidomide-O-PEG4-amine | [CAS]
2401832-00-4 | [Synonyms]
Thalidomide-O-PEG4-NH2
Thalidomide-O-PEG4-amine
4-((14-amino-3,6,9,12-tetraoxatetradecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [Molecular Formula]
C23H31N3O9 | [MDL Number]
MFCD32670308 | [MOL File]
2401832-00-4.mol | [Molecular Weight]
493.51 |
| Hazard Information | Back Directory | [Description]
Thalidomide-O-PEG4-Amine is synthesized compound that can react with NHS ester group or carboxylic acid in the presence of EDC or HATU | [Uses]
Thalidomide-O-PEG4-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | [IC 50]
Cereblon | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Wuhan Topule
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| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
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