| Identification | Back Directory | [Name]
VH032-C4-NH2 dihydrochloride | [CAS]
2341796-78-7 | [Synonyms]
VH 032 amide-alkylC4-amine
VH032-C4-NH2 dihydrochloride
(S,R,S)-AHPC-C4-NH2 dihydrochloride
(2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride | [Molecular Formula]
C27H40ClN5O4S | [MDL Number]
MFCD33029232 | [MOL File]
2341796-78-7.mol | [Molecular Weight]
566.16 |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1]. | [IC 50]
VHL | [storage]
Store at -20°C | [References]
[1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004 |
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