| Identification | More | [Name]
(S)-1-Boc-2-cyanopyrrolidine | [CAS]
228244-04-0 | [Synonyms]
1-BOC-2-CYANO-PYRROLIDINE
1-N-BOC-2-CYANO-PYRROLIDINE
1-n-boc-2-pyrrolidinonitrile
2-CYANO-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
2-CYANOPYRROLIDINE, N-BOC PROTECTED
TERT-BUTYL 2-CYANOPYRROLIDINE-1-CARBOXYLATE
(s)-N-boc-2-cyano-piperidine
(S)-1-(tert-Butoxycarbonyl)-2-Pyrrolidinecarbonitrile
(S)-1-Boc-2-cyanopyrrolidine
(S)-1-BOC-2-Pyrrolidinecarbonitrile
(S)-1-Boc-2-cyanopiperidine | [Molecular Formula]
C10H16N2O2 | [MDL Number]
MFCD01861225 | [Molecular Weight]
196.25 | [MOL File]
228244-04-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
33-36°C | [alpha ]
-105.5 º (c=1, chloroform) | [Boiling point ]
307.9±35.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [Fp ]
>110°C | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
-4.97±0.40(Predicted) | [optical activity]
[α]20/D 105.5°, c = 1 in chloroform | [Water Solubility ]
Slightly soluble in water. | [Sensitive ]
Moisture & Light Sensitive | [InChIKey]
MDMSZBHMBCNYNO-QMMMGPOBSA-N | [CAS DataBase Reference]
228244-04-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
3439 | [WGK Germany ]
3 | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Uses]
(S)-(-)-1-Boc-2-pyrrolidinecarbonitrile is used in synthesis of prolyl oligopeptidase inhibitors and is a reagent that is used in the design of potent and selective inhibitors of DPP-4 that exhibits an attractive pharmacokinetic profile as antidiabetics. | [Uses]
Used in synthesis of prolyl oligopeptidase inhibitors. |
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