| Identification | More | [Name]
(+/-)-NICOTINE | [CAS]
22083-74-5 | [Synonyms]
1-METHYL-2-(3-PYRIDYL)PYRROLIDINE
BLACK LEAF 40
(+/-)-NICOTINE
NICOTINE
(+-)-nicotin
(+-)-pyridin
(r,s)-nicotine
3-(1-methyl-2-pyrrolidinyl)-pyridin
3-(1-methyl-pyrrolidin-2-yl)-pyridine
dl-beta-nicotine
dl-nicotine
(-)-1-Methyl-2-[3-pyridyl]pyrrolidine, free base
R-(+)-Nicotine, [+]-1-Methyl-2-[3-pyridyl]pyrrolidine, Free Base
NICOTINE ALKALOID 95%
NICOTINE ALKALOID USP
DL-Nicotine-d3 (N-methyl-d3)
Nicotine salts: (d1-beta-Nicotine: DL-Nicotine)
(+)-3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine
(2R)-1-Methyl-2-(3-pyridyl)pyrrolidine
3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine | [Molecular Formula]
C10H14N2 | [MDL Number]
MFCD00065370 | [Molecular Weight]
162.23 | [MOL File]
22083-74-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Colourless Liquid | [Melting point ]
-79 °C | [Boiling point ]
67°C/0.5 mm | [density ]
1.02 g/mL at 25 °C(lit.)
| [Fp ]
101 °C | [storage temp. ]
Refrigerator | [solubility ]
ethanol: 50 mg/mL
| [form ]
liquid
| [pka]
8.02(at 25℃) | [color ]
yellow
| [optical activity]
[α]25/D 0°(lit.) | [Usage]
This is the unnatural isomer of Nicotine | [BRN ]
82108 | [Stability:]
Air Sensitive | [CAS DataBase Reference]
22083-74-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T+,N | [Risk Statements ]
R25:Toxic if swallowed.
R27:Very Toxic in contact with skin.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 1654 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
QS5257500
|
| Hazard Information | Back Directory | [Chemical Properties]
(+/-)-NICOTINE is Colourless Liquid
| [Uses]
(+/-)-NICOTINE is an alkaloid isolated from plants. It is an active stimulant, having both addictive and carcinogenic properties.
| [Uses]
Nicotine is an alkaloid isolated from plants. Nicotine is an active stimulant, having both addictive and carcinogenic properties. Nicotine can be absorbed through the alimentary canal, respiratory tra
ct and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic. | [Uses]
This is the unnatural isomer of Nicotine | [Definition]
ChEBI: 3-(1-methylpyrrolidin-2-yl)pyridine is an N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2. It is a N-alkylpyrrolidine, a pyridine alkaloid and a pyrrolidine alkaloid. | [Biochem/physiol Actions]
Prototype nicotinic acetylcholine receptor agonist. | [storage]
Store at -20°C | [Purification Methods]
(+/-)-NICOTINE is purified by fractional distillation. Its solubility in EtOH is ~5%. The picrate forms yellow needles from hot H2O and has m 219o. The methiodide has m 219o (from MeOH). [Craig J Am Chem Soc 55 2854 1933, Nakane & Hutchinson J Org Chem 43 3922 1978, Beilstein 23/6 V 64.] POISONOUS.
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