| Identification | Back Directory | [Name]
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE | [CAS]
21561-09-1 | [Synonyms]
WHI-P258
JAK3 INHIBITOR, NEGATIVE CONTROL
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE
6,7-dimethoxy-N-phenylquinazolin-4-amine
4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-
N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE
JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258 | [Molecular Formula]
C16H15N3O2 | [MDL Number]
MFCD01815294 | [MOL File]
21561-09-1.mol | [Molecular Weight]
281.31 |
| Chemical Properties | Back Directory | [Boiling point ]
441.2±40.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml | [form ]
A crystalline solid | [pka]
6.19±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication. | [Uses]
4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3). | [storage]
Store at -20°C |
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China Langchem Inc.
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0086-21-58956006 |
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| Company Name: |
D&C Chemicals
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+86-21-58447131 |
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