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ChemicalBook--->CAS DataBase List--->215174-50-8

215174-50-8

215174-50-8 Structure

215174-50-8 Structure
IdentificationBack Directory
[Name]

rimacalib
[CAS]

215174-50-8
[Synonyms]

SMP 114
rimacalib
4-Morpholinecarboximidamide, N-[3-[(1S)-1-(2-fluoro[1,1'-biphenyl]-4-yl)ethyl]-5-isoxazolyl]-
[Molecular Formula]

C22H23FN4O2
[MDL Number]

MFCD30747864
[MOL File]

215174-50-8.mol
[Molecular Weight]

394.44
Chemical PropertiesBack Directory
[Melting point ]

>56°C (dec.)
[Boiling point ]

528.8±60.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

8?+-.0.20(Predicted)
[color ]

Off-White to Light Orange
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Rimacalib, an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
[storage]

Store at -20°C
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