Identification | More | [Name]
6-Chloropurine riboside | [CAS]
2004-06-0 | [Synonyms]
6-CHLORO-9-BETA-D-RIBOFURANOSYL-9H-PURINE 6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE 6-CHLOROINOSINE 6-CHLOROPURINE-9-BETA-D-RIBOFURANOSIDE 6-CHLOROPURINE-9-RIBOSIDE 6-CHLOROPURINE NUCLEOSIDE 6-CHLOROPURINE RIBOSIDE 6-CLPR 6-chloropurineribonucleoside 6-chloro-9-ribofuranosyl-9H-purine 6-Chloropurine riboside, pure, 99+% 6-Chloro-9-(b-D-ribofuranosyl)purine 6-Chloropurine ribose 6-CHLOROPURINE RIBOSIDE 98+% 6-Chloropurine riboside 9H-PURINE,6-CHLORO-9-RIBOFURANOSYL 6-Chlrorpurine riboside 6-CHLOROPURINE RIBOSIDE extrapure (2R,3R,4S,5R)-2-(6-Chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | [EINECS(EC#)]
217-904-8 | [Molecular Formula]
C10H11ClN4O4 | [MDL Number]
MFCD00005738 | [Molecular Weight]
286.67 | [MOL File]
2004-06-0.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
158-162 °C (dec.)(lit.) | [Boiling point ]
614.8±65.0 °C(Predicted) | [density ]
1.7303 (rough estimate) | [refractive index ]
-45 ° (C=0.8, H2O) | [storage temp. ]
2-8°C
| [form ]
Powder | [pka]
13.06±0.70(Predicted) | [color ]
Yellow to Green | [Detection Methods]
HPLC,NMR | [CAS DataBase Reference]
2004-06-0(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . S36:Wear suitable protective clothing . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RTECS ]
UO7520800 | [F ]
10-23 | [Hazard Note ]
Irritant | [HS Code ]
29389090 |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
6-CHLOROPURINE RIBOSIDE acts as a reactant in the synthesis of isozyme-specific enzyme inhibitors as well as in the preparation of dog coronary artery receptor agonists. | [Purification Methods]
Purify the riboside by suspending the dry solid (~12 g) in hot MeOH (130 mL) and then adding enough hot H2O (~560mL) to cause solution, filter and set aside at 5o overnight. The colourless crystals of the riboside are filtered off, washed with Me2CO, Et2O and dried at 60o/0.1mm. More material can be obtained by evaporating the filtrate to dryness and recrystallisation of the residue from MeOH/H2O (2:1) (15mL/g). It has max 264nm ( 9140) in H2O. [Robins Biochemical Preparations 10 145 1963, Baker et al. J Org Chem 22 954 1957.] |
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