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ChemicalBook--->CAS DataBase List--->2000-43-3

2000-43-3

2000-43-3 Structure

2000-43-3 Structure
IdentificationMore
[Name]

2,2,2-Trichloro-1-phenylethanol
[CAS]

2000-43-3
[Synonyms]

1-PHENYL-2,2,2-TRICHLOROETHANOL
2,2,2-TRICHLORO-1-PHENYLETHANOL
A,A,A-TRICHLOROMETHYLPHENYLCARBINOL
A-(TRICHLOROMETHYL)BENZYL ALCOHOL
AURORA KA-7035
TIMTEC-BB SBB008085
alpha-(trichloromethyl)-benzenemethano
alpha-(trichloromethyl)benzenemethanol
alpha-(trichloromethyl)-benzylalcoho
alpha-(trichloromethyl)benzylalcohol
efiran99
phenyl(trichloromethyl)carbinol
trichloromethylphenylcarbinol
[EINECS(EC#)]

217-887-7
[Molecular Formula]

C8H7Cl3O
[MDL Number]

MFCD00043571
[Molecular Weight]

225.5
[MOL File]

2000-43-3.mol
Chemical PropertiesBack Directory
[Melting point ]

37 °C
[Boiling point ]

93-96°C 0,8mm
[density ]

1.4250 (rough estimate)
[refractive index ]

1.5690
[Fp ]

93-96°C/0.8mm
[storage temp. ]

2-8°C
[pka]

11.92±0.20(Predicted)
[Water Solubility ]

Not miscible in water.
[BRN ]

510385
[CAS DataBase Reference]

2000-43-3(CAS DataBase Reference)
[EPA Substance Registry System]

2000-43-3(EPA Substance)
Safety DataBack Directory
[Risk Statements ]

R36/38:Irritating to eyes and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[RTECS ]

DP1325000
[TSCA ]

Yes
[Toxicity]

LDLo scu-rat: 790 mg/kg JPETAB 24,405,24
Hazard InformationBack Directory
[Physical properties]

Colorless, slightly viscous liquid. Almost insoluble in water, soluble in alcohol and oils. Very faint, metallic-green, musty-floral odor of good tenacity.
[Uses]

2,2,2-Trichloro-1-phenylethanol is used as pharmaceutical intermediate.
[Production Methods]

2,2,2-Trichloro-1-phenylethanol can be produced 1) from Chloral with Aluminum trichloride in Benzene. 2) from Benzaldehyde and Chloroform.
[Synthesis Reference(s)]

Canadian Journal of Chemistry, 58, p. 485, 1980
Tetrahedron Letters, 19, p. 1521, 1978 DOI: 10.1016/S0040-4039(01)94592-7
[Safety Profile]

Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of Clí.
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

2,2,2-Trichloro-1-phenylethanol, 98%(2000-43-3)
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