| Identification | More | [Name]
Ethyl 3-(4-fluorophenyl)-3-oxopropanoate | [CAS]
1999-00-4 | [Synonyms]
3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
(4-FLUOROBENZOYL)ACETIC ACID ETHYL ESTER
ETHYL 3-(4-FLUOROPHENYL)-3-OXOPROPANOATE
ETHYL 3-(4'-FLUOROPHENYL)-3-OXOPROPNOATE
ETHYL 4-FLUOROBENZOYLACETATE
ETHYL (P-FLUOROBENZOYL)ACETATE
3-(4'-Fluorophenyl)-3-oxopropanoate
3-Oxo-3-(4-fluorophenyl)propanoic acid ethyl ester
p-Fluorobenzoylacetic acid ethyl ester
β-Oxo-4-fluorobenzenepropionic acid ethyl ester | [Molecular Formula]
C11H11FO3 | [MDL Number]
MFCD03093631 | [Molecular Weight]
210.2 | [MOL File]
1999-00-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
117-120℃ | [Boiling point ]
117-120 °C(lit.) | [density ]
1.174 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.5040(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [pka]
9.82±0.25(Predicted) | [Specific Gravity]
1.19 | [InChIKey]
SJUXLKYJKQBZLM-UHFFFAOYSA-N | [CAS DataBase Reference]
1999-00-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
Reactant used as a precursor in:
- Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines for possible use as antimalarial treatments
- Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones
- Oxidative cross-coupling with indoles via dioxygen activation
- Cyclization of keto esters for synthesis of pyrones
- Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives
- Conia-ene reactions for synthesis of methylenecyclopentane derivatives
| [General Description]
Ethyl (4-fluorobenzoyl)acetate on condensation with benzofurazan oxide yields 2-(carboethoxy)-3-(4′-fluoro)phenylquinoxaline1,4-dioxide. |
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