| Identification | Back Directory | [Name]
GW7604 | [CAS]
195611-82-6 | [Synonyms]
GW7604
2-Propenoic acid, 3-[4-[(1E)-1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenyl]-, (2E)- | [Molecular Formula]
C25H22O3 | [MDL Number]
MFCD29770803 | [MOL File]
195611-82-6.mol | [Molecular Weight]
370.44 |
| Hazard Information | Back Directory | [Uses]
(E)-GW7604 is the (E)-isomer of GW7604, an antiestrogen and a metabolite of GW5638 (HY-112746), which is a high-affinity estrogen receptor (ER) antagonist[1]. | [References]
[1] Willson TM, et al. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology. 1997 Sep;138(9):3901-11. DOI:10.1210/endo.138.9.5358 |
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