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ChemicalBook--->CAS DataBase List--->194665-85-5

194665-85-5

194665-85-5 Structure

194665-85-5 Structure
IdentificationBack Directory
[Name]

GATX2
[CAS]

194665-85-5
[Synonyms]

GATX2
Leiuropeptide II (9CI)
[Molecular Formula]

C125H199N39O47S6
[MOL File]

194665-85-5.mol
[Molecular Weight]

3192.54
Chemical PropertiesBack Directory
[density ]

1.65±0.1 g/cm3(Predicted)
[form ]

Powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 1 mg/ml in water
Hazard InformationBack Directory
[Uses]

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent?KD?of ～20 pM. GaTx2 is a peptide toxin inhibitor?from?Leiurus quinquestriatus hebraeus?venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types[1].
[References]

[1] Christopher H Thompson, et al. Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels.J Biol Chem DOI:10.1074/jbc.M109.031724
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