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ChemicalBook--->CAS DataBase List--->68893-82-3

68893-82-3

68893-82-3 Structure

68893-82-3 Structure
IdentificationBack Directory
[Name]

PTH (1-84) (HUMAN)
[CAS]

68893-82-3
[Synonyms]

PREOS
rhPTH
Preotact
PTH, HUMAN
Human PTH(1-84)
PTH (HUMAN, 1-84)
PTH (1-84) (HUMAN)
Parathormone, PTH
Parathormone (human)
PTH (human) TFA Salt
PARATHYROID HORMONE HUMAN
Human parathormone (1-84)
Human parathyroid hormone
parathyroid hormone(1-84)
Rabbit Parathyroid hormone
Human parathyroid hormone(1-84)
PARATHYROID HORMONE (HUMAN, 1-84)
PARATHYROID HORMONE (1-84) (HUMAN)
Parathyroid hormone human, 95%(HPLC)
Recombinant human parathyroid hormone
PARATHYROID HORMONE(1-84) HUMAN 50 UG*
SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-VAL-ALA-LEU-GLY-ALA-PRO-LEU-ALA-PRO-ARG-ASP-ALA-GLY-SER-GLN-ARG-PRO-ARG-LYS-LYS-GLU-ASP-ASN-VAL-LEU-VAL-GLU-SER-HIS-GLU-LYS-SER-LEU-GLY-GLU-ALA-ASP-LYS-ALA-ASP-VAL-ASN-VAL-LEU-THR-LYS-ALA-LYS-SER-GLN
H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-VAL-ALA-LEU-GLY-ALA-PRO-LEU-ALA-PRO-ARG-ASP-ALA-GLY-SER-GLN-ARG-PRO-ARG-LYS-LYS-GLU-ASP-ASN-VAL-LEU-VAL-GLU-SER-HIS-GLU-LYS-SER-LEU-GLY-GLU-ALA-ASP-LYS-ALA-ASP-VAL-ASN-VAL-LEU-THR-LYS-ALA-LYS-SER-GLN-OH
[EINECS(EC#)]

282-361-6
[Molecular Formula]

C408H674N126O126S2
[MDL Number]

MFCD00081830
[Molecular Weight]

9424.62
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

powder
[Water Solubility ]

water: 1mg/mL, clear, colorless
Safety DataBack Directory
[Hazard Codes ]

B
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[F ]

10-21
Hazard InformationBack Directory
[Uses]

Treatment of osteoporosis, as an antiosteoporotic, in the treatment of bone and mineral disease and disorders, bone metabolism regulator, blood calcium regulator, and as a diagnostic aid (pseudohypoparathyroidism; hypocalcemia).
[Indications]

Human rPTH (1-34) has been produced by recombinant technologies, is now approved, and will soon be available for the treatment of osteoporosis. It is given subcutaneously, 25 μg/day cyclically for 12 to 18 months, to increase bone density in individuals with a history of fractures, severe osteopenia, or osteoporosis. PTHrP (1-36) has also been synthesized and is in early clinical trials.
[Brand name]

Paroidin (Parke-Davis).
[Biological Activity]

Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidismrespectively.
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