Identification | Back Directory | [Name]
nicotinic acid ribonucleoside | [CAS]
17720-18-2 | [Synonyms]
Nicotinic Riboside NARH - oxidized form nicotinic acid ribonucleoside 3-Carboxy-1-β-D-ribofuranosylpyridiniuM Inner Salt 3-Carboxy-1-β-D-ribofuranosyl-
pyridiniuM Hydroxide Inner Salt 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate | [Molecular Formula]
C11H13NO6 | [MDL Number]
MFCD30730071 | [MOL File]
17720-18-2.mol | [Molecular Weight]
255.224 |
Chemical Properties | Back Directory | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
Water : 62.5 mg/mL (244.89 mM; Need ultrasonic) | [Stability:]
Hygroscopic | [InChI]
InChI=1/C11H13NO6/c13-5-7-8(14)9(15)10(18-7)12-3-1-2-6(4-12)11(16)17/h1-4,7-10,13-15H,5H2/t7-,8?,9?,10-/s3 | [InChIKey]
PUEDDPCUCPRQNY-KGCVILSVNA-N | [SMILES]
C1(O)[C@@H](CO)O[C@@H]([n+]2cccc(C([O-])=O)c2)C1O |&1:2,6,r| |
Hazard Information | Back Directory | [Description]
Nicotinic acid riboside(17720-18-2) are vitamin B3 precursors NAD+ in human diet. NAD+ has a fundamental importance for cellular biology, that derives from its essential role as a cofactor various metabolic redox reactions, as well as an obligate co-substrate for NAD+-consuming enzymes which are involved in many fundamental cellular processes including aging/longevity[1].
| [Chemical Properties]
White Solid | [Uses]
An effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells. | [Definition]
ChEBI: D-ribosylnicotinate is conjugate base of D-ribosylnicotinic acid. It has a role as a human metabolite. It is a conjugate base of a D-ribosylnicotinic acid. | [References]
[1] ORLANDIIVAN; VaiMarina; AlberghinaLilia. Nicotinamide, Nicotinamide Riboside and Nicotinic Acid-Emerging Roles in Replicative and Chronological Aging in Yeast.[J]. Biomolecules, 2020, 10 4. DOI:10.3390/biom10040604. |
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