| Identification | More | [Name]
D(+)-Galactosamine hydrochloride | [CAS]
1772-03-8 | [Synonyms]
2-AMINO-2-DEOXY-D-GALACTOPYRANOSE HYDROCHLORIDE
2-AMINO-2-DEOXY-D-GALACTOSE
2-AMINO-2-DEOXY-D-GALACTOSE HYDROCHLORIDE
2-AMINO-3-DEOXY-D-GALACTOSE HYDROCHLORIDE
2-AMINO-D-GALACTOSE HYDROCHLORIDE
CHONDROSAMINE
CHONDROSAMINE HYDROCHLORIDE
D-2-GALACTOSAMINE HYDROCHLORIDE
D-CHONDROSAMINE HCL
D-CHONDROSAMINE HYDROCHLORIDE
D-GALACTOSAMINE HCL
D(+)-GALACTOSAMINE HYDROCHLORIDE
D-GALACTOSAMINE HYDROCHLORIDE
D-GALN HCL
GALACTOSAMINE HCL
GALACTOSAMINE HCL, D-
GALACTOSAMINE HYDROCHLORIDE
2-amino-2-deoxy-,hydrochloride,d-galactos
2-amino-2-deoxy-d-galactoshydrochloride
D(+)Galactosamine hydrochloride D-Chondrosamine hydrochloride | [EINECS(EC#)]
217-198-1 | [Molecular Formula]
C6H14ClNO5 | [MDL Number]
MFCD00135830 | [Molecular Weight]
215.63 | [MOL File]
1772-03-8.mol |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
182-185 °C (dec.)(lit.)
| [alpha ]
96 º (589nm c=1,H2O,24 hrs) | [density ]
1.3965 (rough estimate) | [refractive index ]
96 ° (C=1, H2O) | [storage temp. ]
Store at 2-8 | [solubility ]
H2O: 50 mg/mL, clear, colorless
| [form ]
White solid | [color ]
White to Off-White | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [Merck ]
14,4334 | [BRN ]
3697825 | [Stability:]
Moisture Sensitive | [CAS DataBase Reference]
1772-03-8(CAS DataBase Reference) | [EPA Substance Registry System]
1772-03-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
LW5500000
| [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
29225000 |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
Specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner. | [General Description]
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards | [Biochem/physiol Actions]
Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF). | [Purification Methods]
Dissolve the hydrochloride in a small volume of H2O. Then add three volumes of EtOH, followed by acetone until faintly turbid and keep overnight in a refrigerator. [Roseman & Ludoweig J Am Chem Soc 76 301 1954, Beilstein 4 IV 2024.] |
|
|