Identification | More | [Name]
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE | [CAS]
17467-15-1 | [Synonyms]
1,2,4-THIADIAZOL-5-AMINE, 3-PHENYL- 3-PHENYL-1,2,4-THIADIAZOL-5-AMINE 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE TIMTEC-BB SBB005511 4-thiadiazol-5-amine,3-phenyl-2 3-phenyl-1,2,4-thiadiazol-5-ylamine 3-Phenyl-1,2,4-triazol-5-ylamine 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE 99% | [EINECS(EC#)]
241-485-0 | [Molecular Formula]
C8H7N3S | [MDL Number]
MFCD00003159 | [Molecular Weight]
177.23 | [MOL File]
17467-15-1.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S22:Do not breathe dust . | [HazardClass ]
IRRITANT | [HS Code ]
29341000 |
Hazard Information | Back Directory | [Description]
5-Amino-3-phenyl-1,2,4-thiadiazole is an important organic synthetic reagent with remarkable reactivity and stability and has been used in the synthesis of a variety of heterocyclic compounds including 1,2,4-triazol-3-ylphenyls, derivatives of 2-aryl-5-amino-thiadiazole, 5-amino-1,2,4-thiadiazol-3-phenyls, and 5 -amino-1,2,4-thiadiazole-3-phenyl-3-methyl derivatives. It is also used in the synthesis of polymers such as poly(5-amino-3-phenyl-1,2,4-thiadiazole). In addition, 5-amino-3-phenyl-1,2,4-thiadiazole is an inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). The compound inhibits the release of pro-inflammatory cytokines such as tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). | [Chemical Properties]
LIGHT BROWNISH FINE CRYSTALLINE POWDER | [Uses]
3-Phenyl-1,2,4-thiadiazol-5-amine is used as a reactant in the preparation of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists. |
Spectrum Detail | Back Directory | [Spectrum Detail]
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)MS 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)1HNMR 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)13CNMR 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)IR1 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)IR2
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