Identification | Back Directory | [Name]
L-SEPIAPTERIN | [CAS]
17094-01-8 | [Synonyms]
SEPIAPTERIN L-SEPIAPTERIN L-Sepiapterin,98% Sepiapterin solid L-SEPIAPTERIN DIHYDRATE L -SEPIAPTERIN DIHYDRATE 99+% SEPIAPTERIN (L-SEPIAPTERIN) COFACTOR OF NITRIC OX 2-amino-6-(2-hydroxypropanoyl)-7,8-dihydro-1H-pty oeridin-4-one 2-AMINO-7,8-DIHYDRO-6-(2S-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE (S)-2-aMino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(1H)-one (S)-2-AMino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one S(-)-2-AMINO-7,8-DIHYDRO-6-(2-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE Sepiapterin,S-()-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridinone, L-Sepiapterin | [Molecular Formula]
C9H11N5O3 | [MDL Number]
MFCD00210214 | [MOL File]
17094-01-8.mol | [Molecular Weight]
237.22 |
Chemical Properties | Back Directory | [Appearance]
yellow to orange powder | [Melting point ]
>270 °C (dec.) | [Boiling point ]
448.1±55.0 °C(Predicted) | [density ]
1.86±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO: 27 mg/mL
| [form ]
solid
| [pka]
12.33±0.20(Predicted) | [color ]
yellow
| [Stability:]
Light Sensitive | [CAS DataBase Reference]
17094-01-8 |
Hazard Information | Back Directory | [Chemical Properties]
yellow to orange powder | [Uses]
L-Sepiapterin serves as a substrate for BH4 synthesis via the pterin salvage pathway. It inhibits rat liver GTP cyclohydrolase with an IC50 value of approximately 25 μM. It can be used to circumvent the inhibition of pterin biosynthesis by 2,4-diamino-6-hydroxy pyrimidine.[Cayman Chemical] | [Definition]
ChEBI: L-sepiapterin is a sepiapterin with L configuration. | [General Description]
Sepiapterin, a pteridine derivative, is a stable precursor of tetrahydrobiopterin (BH4). It is a yellow pigment found in sepia mutant of Drosophila melanogaster and lemon Bombyx mori mutant (silkworm). | [Biochem/physiol Actions]
Cofactor of nitric oxide synthase; intracellularly converted to tetrahydro-biopterin leading to the stimulation of nitric oxide. | [storage]
Store at -20°C |
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