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ChemicalBook--->CAS DataBase List--->169332-60-9

169332-60-9

169332-60-9 Structure

169332-60-9 Structure
IdentificationBack Directory
[Name]

AC-DEVD-CHO
[CAS]

169332-60-9
[Synonyms]

MF 191
AC-DEVD-CHO
AC-DEVD-ALDEHYDE
AC-DEVD-CHO?, >98%
CASPASE-3 INHIBITOR
Ac-Asp-Glu-Val-Asp-H
ACETYL-DEVD-ALDEHYDE
CASPASE-3 INHIBITOR I
AC-DEVD-CHO USP/EP/BP
AC-ASP-GLU-VAL-ASP-CHO
CPP32/APOPAIN INHIBITOR
N-AC-ASP-GLU-VAL-ASP-CHO
N-ACETYL-ASP-GLU-VAL-ASP-AL
AC-ASP-GLU-VAL-ASP-ALDEHYDE
N-acetyl-Asp-Glu-Val-Asp-Ala
CASPASE-3 INHIBITOR (ALDEHYDE)
ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE
AC-ASP-GLU-VAL-ASP-H (ALDEHYDE)
CASPASE 3 (APOPAIN) INHIBITOR 1
Acetyl-aspartyl-glutamyl-valyl-aspartal
Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al
N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE)
AC-ASP-GLU-VAL-ASP-ALDEHYDE (PSEUDO ACID)
N-Acetyl-Asp-Glu-Val-Asp-al >=95%, powder
Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%
ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPART-1-AL
Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem
L-Valinamide, N-acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-
N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE
CASPASE-3 INHIBITOR I;N-AC-ASP-GLU-VAL-ASP-CHO;ACETYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTAL
(4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxyMethyl)-13-forMyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
[Molecular Formula]

C20H30N4O11
[MDL Number]

MFCD00671412
[MOL File]

169332-60-9.mol
[Molecular Weight]

502.47
Chemical PropertiesBack Directory
[Boiling point ]

1021.1±65.0 °C(Predicted)
[density ]

1.374±0.06 g/cm3(Predicted)
[RTECS ]

EK7643000
[storage temp. ]

-20°C
[solubility ]

H2O: 1 mg/mL
[form ]

powder
[pka]

4.19±0.10(Predicted)
[color ]

white
[biological source]

synthetic
[Water Solubility ]

H2O: 1mg/mL
[Sensitive ]

Moisture Sensitive
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.
[Uses]

Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase
[Definition]

ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.
[General Description]

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.
[Biochem/physiol Actions]

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
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