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ChemicalBook--->CAS DataBase List--->16078-30-1

16078-30-1

16078-30-1 Structure

16078-30-1 Structure
IdentificationMore
[Name]

1-ACETYLINDOLINE
[CAS]

16078-30-1
[Synonyms]

1-(2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE
1-(2,3-DIHYDRO-INDOL-1-YL)-ETHANONE
1-ACETYL-2,3-DIHYDROINDOLE
1-ACETYLINDOLINE
N-ACETYL INDOLINE
1-acetyl-2,3-dihydro-1h-indol
1-acetyl-indolin
Acetylindoline,N-
1H-Indole, 1-acetyl-2,3-dihydro-(9CI)
1-ACETYLINDOLINE 98+%
1-Acetyl-2,3-dihydro-1H-indole
[Molecular Formula]

C10H11NO
[MDL Number]

MFCD00022908
[Molecular Weight]

161.2
[MOL File]

16078-30-1.mol
Chemical PropertiesBack Directory
[Melting point ]

102-104 °C(lit.)
[Boiling point ]

125-130 °C(Press: 1 Torr)
[density ]

1.144±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[pka]

1.13±0.20(Predicted)
[CAS DataBase Reference]

16078-30-1(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[RTECS ]

NM1892500
[HS Code ]

2933998090
Hazard InformationBack Directory
[Uses]

• ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5
[Uses]

  • Reactant for preparation of triazolothiadiazepine dioxide derivatives
  • Reactant for preparation of halo-substituted aromatic amides
  • Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
  • Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
  • Reactant for regioselective ortho Suzuki-Miyaura coupling reaction
[Uses]

1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone.
[Synthesis Reference(s)]

Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9
Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1
[General Description]

1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported.
Spectrum DetailBack Directory
[Spectrum Detail]

1-ACETYLINDOLINE(16078-30-1)1HNMR
1-ACETYLINDOLINE(16078-30-1)Raman
1-ACETYLINDOLINE(16078-30-1)IR
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

1-Acetylindoline, 98+%(16078-30-1)
[Sigma Aldrich]

16078-30-1(sigmaaldrich)
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