| Identification | More | [Name]
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate | [CAS]
156311-83-0 | [Synonyms]
(7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE
7-AZABENZOTRIAZOL-1-YLOXY-TRIS-(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE
(7-AZABENZOTRIAZOLE-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE
PYAOP
(7-AZABENZOTRIAZOLE-1-YLOXY)TRIPYRROLIDI
(7-Azabenzotriazol-1-yloxy)tripyrrolidinophospho
PY (7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate
PVP-VACOPOLYMERSERIES
PYAOP ((7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE)
3H-1,2,3-triazolo[4,5-b]pyridine phosphonium derivative | [EINECS(EC#)]
627-192-4 | [Molecular Formula]
C17H27F6N7OP2 | [MDL Number]
MFCD03703417 | [Molecular Weight]
521.38 | [MOL File]
156311-83-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
163-168 °C(lit.) | [RTECS ]
TH3890000 | [storage temp. ]
-20°C | [solubility ]
Soluble in water or 1% acetic acid | [form ]
Powder or Crystalline Powder | [color ]
White to off-white | [Water Solubility ]
Soluble in water. | [InChI]
InChI=1S/C17H27N7OP.F6P/c1-2-11-21(10-1)26(22-12-3-4-13-22,23-14-5-6-15-23)25-24-17-16(19-20-24)8-7-9-18-17;1-7(2,3,4,5)6/h7-9H,1-6,10-15H2;/q+1;-1 | [InChIKey]
CBZAHNDHLWAZQC-UHFFFAOYSA-N | [SMILES]
[P+5]([F-])([F-])([F-])([F-])([F-])[F-].[P+](N1CCCC1)(N1CCCC1)(N1CCCC1)ON1N=NC2C=CC=NC1=2 | [CAS DataBase Reference]
156311-83-0(CAS DataBase Reference) | [EPA Substance Registry System]
Phosphorus(1+), [3-(hydroxy-.kappa.O)-3H-1,2,3-triazolo[4,5-b]pyridinato]tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1) (156311-83-0) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate is white to off-white crystalline powder
| [Uses]
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate is used as a coupling reagent in solid phase peptide synthesis. It is preferred over HATU, because it does not side react at the N-terminus of the peptide. Compared to the HOBt derivates, PyAOP (and HOAt in general) are more reactive due to the additional nitrogen.
| [Uses]
PyAOP is a phosphonium salt used as a coupling reagent in solid-phase peptide synthesis, without undergoing side reactions with the amino terminus. PyAOP is a derivative of HOAt (H805070). | [reaction suitability]
reaction type: Coupling Reactions |
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