Identification | More | [Name]
Dodecyltriphenylphosphonium bromide | [CAS]
15510-55-1 | [Synonyms]
(1-DODECYL)TRIPHENYLPHOSPHONIUM BROMIDE DODECYLTRIPHENYLPHOSPHONIUM BROMIDE N-DODECYL TRIPHENYLPHOSPHONIUM BROMIDE Lauryltriphenylphosphonium bromide (1-Dodecyl)Triphenylphosphonium Chloride n-Dodecyl triphenylphosphonium bromide, 98+% dodecyltriphenylphosphonium (1-DODECYL)TRIPHENYLPHOSPHONIUM BROMIDE, 98+% PHOSPHONIUM,DODECYLTRIPHENYL-,BROMIDE Triphenyl(dodecyl)phosphonium·bromide Triphenyldodecylphosphonium·bromide Triphenyl(dodecyl)phosphonium Triphenyldodecylphosphonium | [EINECS(EC#)]
239-538-8 | [Molecular Formula]
C30H40BrP | [MDL Number]
MFCD00031546 | [Molecular Weight]
511.52 | [MOL File]
15510-55-1.mol |
Chemical Properties | Back Directory | [Melting point ]
85-88 °C(lit.) | [storage temp. ]
RT | [solubility ]
Soluble in DMSO (50 mg/ml) or ethanol (25 mg/mL) | [form ]
solid | [color ]
White | [Sensitive ]
Hygroscopic | [BRN ]
3581921 | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. | [CAS DataBase Reference]
15510-55-1(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
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Hazard Information | Back Directory | [Description]
Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2 | [Definition]
ChEBI: An organic bromide salt that containing equal numbers of dodecyl(triphenyl)phosphonium cations and bromide anions. | [References]
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