| Identification | More | [Name]
ETHYL 2-FLUOROACETOACETATE | [CAS]
1522-41-4 | [Synonyms]
2-FLUORO-3-OXO-BUTANOIC ACID ETHYL ESTER
2-FLUORO-3-OXO-BUTYRIC ACID ETHYL ESTER
BUTYRIC ACID, 2-FLUORO-3-OXO-, ETHYL ESTER
ETHYL-2-FLUORO-3-OXOBUTANOATE
ETHYL 2-FLUORO-3-OXOBUTYRATE
ETHYL 2-FLUOROACETOACETATE
FLUOROACETOACETIC ACID ETHYL ESTER
2-Fluoroacetoacetic Acid Ethyl Ester
α-Fluoro-β-oxobutyric acid ethyl ester
Ethy 2-fluoroacetoacetate | [EINECS(EC#)]
629-671-3 | [Molecular Formula]
C6H9FO3 | [MDL Number]
MFCD00215830 | [Molecular Weight]
148.13 | [MOL File]
1522-41-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless liquid | [Boiling point ]
183 °C (lit.) | [density ]
1.181 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.414(lit.)
| [Fp ]
194 °F
| [form ]
Liquid | [pka]
9.25±0.46(Predicted) | [color ]
Clear colorless to pale yellow | [InChIKey]
SHTFQLHOTAJQRJ-UHFFFAOYSA-N | [CAS DataBase Reference]
1522-41-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29183000 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless liquid | [Uses]
Reactant for:
- Michael addition-induced cyclization reaction
- Asymmetric Mannich reaction
- Enantioselective organocatalytic conjugate addition
| [Synthesis Reference(s)]
Tetrahedron, 54, p. 2867, 1998 DOI: 10.1016/S0040-4020(98)83023-8 | [General Description]
Ethyl 2-fluoroacetoacetate is an α-fluorinated β-keto ester that can be prepared by the fluorination of ethyl acetoacetate. |
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