| Identification | More | [Name]
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID | [CAS]
149676-40-4 | [Synonyms]
1-ETHYL-6-FLUORO-1,4-DIHYDRO-7-(4-METHYL-1-PIPERAZINYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID) METHANE SULPHONATE DIHYDRATE
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
EU-5306
PEFLOXACIN
PEFLOXACINE MESYLATE DIHYDRATE
PEFLOXACINE METHANSULFONATE DIHYDRATE
PEFLOXACIN MESYLATE
PEFLOXACIN MESYLATE DIHYDRATE
PEFLOXACIN METHANESULFONATE
PEFLOXACIN METHANE SULFONATE DIHYDRATE
PERFLOXACINE
RB-1589
Pefloxacin dihydrate mesylate
Pefloxacine monomethanesulfonate dihydrate, Pefloxacinium methanesulfonate dihydrate, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate | [EINECS(EC#)]
274-613-9 | [Molecular Formula]
C18H28FN3O8S | [MDL Number]
MFCD01685696 | [Molecular Weight]
465.49 | [MOL File]
149676-40-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3 | [RTECS ]
VB2002200 | [HS Code ]
29335990 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
antifungal, calmodulin antagonist | [Uses]
Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase. | [Biological Activity]
Pefloxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IVwhich are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosomesupercoilingand resealing. ThereforeDNA replication and transcription is inhibited . Pefloxacin is an analog of norfloxacin. |
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