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ChemicalBook--->CAS DataBase List--->1486482-16-9

1486482-16-9

1486482-16-9 Structure

1486482-16-9 Structure
IdentificationBack Directory
[Name]

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
[CAS]

1486482-16-9
[Synonyms]

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
[Molecular Formula]

C17H13Cl2N3O4S
[MDL Number]

MFCD28411402
[MOL File]

1486482-16-9.mol
[Molecular Weight]

426.274
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 250 mg/mL (586.48 mM; Need ultrasonic)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. ML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity[1].
[References]

[1]. Brimacombe KR, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013;5(1):12-17.
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