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ChemicalBook--->CAS DataBase List--->1357171-62-0

1357171-62-0

1357171-62-0 Structure

1357171-62-0 Structure
IdentificationBack Directory
[Name]

ML-228
[CAS]

1357171-62-0
[Synonyms]

L-228
ML-228
CID-46742353
ML228; ML 228
ML-228;CID-46742353
N-([1,1'Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine
N-([1,1-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-
[Molecular Formula]

C27H21N5
[MDL Number]

MFCD26792570
[MOL File]

1357171-62-0.mol
[Molecular Weight]

415.49
Chemical PropertiesBack Directory
[Boiling point ]

686.0±65.0 °C(Predicted)
[density ]

1.228±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C, Inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

2.03±0.63(Predicted)
[color ]

Pale Yellow to Light Yellow
Hazard InformationBack Directory
[Uses]

N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway.
[Definition]

ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines.
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