| Identification | More | [Name]
(R)-MOP | [CAS]
145964-33-6 | [Synonyms]
(R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL
(R)-(+)-MOP
(R)-MOP
(S)-(-)-2-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL
(S)-2-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL
(S)-(-)-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL
(S)-(-)-MOP
(S)-MOP
(R)-(+)-2-(diphenylphosphino)-2’-methoxy-21,1’-binaphthyl(r-mop)
(R)-2-(diphenylphosphino)-2'-methoxy-1,1'-binaphthyl (R)-MOP
(R)-(+)-2-(Diphenylphosphino)-2'-methoxy-1,1'-binaphthyl,99%(R)-MOP
(R)-(2'-Methoxy[1,1'-binaphthalen]-2-yl)diphenyl-phosphine | [Molecular Formula]
C33H25OP | [MDL Number]
MFCD00269686 | [Molecular Weight]
468.52 | [MOL File]
145964-33-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
177-179°C | [alpha ]
+67° ±2° (c 1, toluene) | [Boiling point ]
584.1±38.0 °C(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
almost transparency in Toluene | [form ]
Powder | [color ]
white | [optical activity]
[α]20/D +94°, c = 0.5 in chloroform | [Sensitive ]
air sensitive | [CAS DataBase Reference]
145964-33-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [HS Code ]
2931.90.6000 |
| Questions and Answers (Q&A) | Back Directory | [Reactions]
1. Efficient catalyst for the enantoselective hydrosilyation of 1-alkenes to optically active 2-alcohols.
2. Ligand for palladium-catalyzed asymmetric reduction of allyltc esters.
3. Ligand for the rhodium-catalyzed asymmetric aryiation of imines with organostannanes.
4. Ligand for the rhodiunvcatalyzed asymmetrk: addition of aryl- and alkenyiborontc acids to Isatins.
5. Ligand for desymmetrizatlon of malonamides via an enantiosetective intramolecular Buchwatd-Hartwig reaction.
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| Hazard Information | Back Directory | [Uses]
(R)-MOP is used as a catalyst in the preparation of chiral tetrahydrobenzofuranone alkylideneboronates and oxindoles. Also used as a catalyst in the total synthesis of Oseltamivir Phosphate (O701000); an orally active inhibitor of influenza virus neuraminidase and an antiviral drug. | [Uses]
Takasago Ligands and Complexes for Asymmetric Reactions
Ligand used in palladium-catalyzed asymmetric hydrosilylation of olefins, palladium-catalyzed reduction of allylic esters, rhodium-catalyzed asymmetric addition reactions, and asymmetric amination reactions catalyzed by copper(I) complexes. | [General Description]
R-MOP is a phosphine ligand with a bis-naphthalene backbone. |
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