| Identification | More | [Name]
BOC-PYR-OET | [CAS]
144978-12-1 | [Synonyms]
1-BOC-L-PYROGLUTAMIC ACID ETHYL ESTER
N-Boc-L-pyroglutamic acid ethyl ester
(S)-N-alpha-t-Butyloxycarbonyl-pyroglutamic acid ethyl ester
Boc-L-Pyr-OEt
N-tert-Butoxycarbonyl-L-pyroglutamic acid ethyl ester
(S)-5-Oxo-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester | [EINECS(EC#)]
604-450-4 | [Molecular Formula]
C12H19NO5 | [MDL Number]
MFCD07778090 | [Molecular Weight]
257.283 | [MOL File]
144978-12-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
52.0 to 56.0 °C | [Boiling point ]
375.0±35.0 °C(Predicted) | [density ]
1.182±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
-4.15±0.40(Predicted) | [color ]
White to Almost white | [InChI]
InChI=1S/C12H19NO5/c1-5-17-10(15)8-6-7-9(14)13(8)11(16)18-12(2,3)4/h8H,5-7H2,1-4H3/t8-/m0/s1 | [InChIKey]
YWWWGFSJHCFVOW-QMMMGPOBSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)C(=O)CC[C@H]1C(OCC)=O | [CAS DataBase Reference]
144978-12-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
N-tert-Butoxycarbonylpyroglutamic Acid Ethyl Ester is a compound derived from pyroglutamic acid, used in the synthesis of various pharmacological compounds. It is used in the synthesis of HCV protesase inhibitors as well as alkyl renin inhibitors. | [General Description]
BOC-PYR-OET [also known as 1-(1,1-Dimethylethyl) 2-ethyl (2S)-5-oxo-1,2-pyrrolidinedicarboxylate] is an organic ester compound that can be used as a pharmaceutical intermediate for the synthesis of drugs such as Avibactam, Velpatasvir and CETP inhibitors (MK-8262). |
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