| Identification | More | [Name]
DEHYDROABIETYLAMINE | [CAS]
1446-61-3 | [Synonyms]
1,4A-DIMETHYL-7-ISOPROPYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENEMETHYLAMINE
1 4A-DIMETHYL-7-ISOPROPYL-1 2 3,4A 9 10 10A-OCTAHYDRO-1-PHENANTHRENE METHYLAMINE
(1R,4AS,10AR)-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-,4A-DIMETHYL-7-(1-METHYLETHYL)-1-PHENANTHRENEMETHANAMINE HYDROCHLORIDE
AMINE D
D(+)-DEHYDROABIETYLAMINE
(+)-DEHYDROABIETHYLAMINE
DEHYDROABIETHYLAMINE
(+)-DEHYDROABIETYLAMINE
DEHYDROABIETYLAMINE
LYLAMINE HYDROCHLORIDE
(1r-(1alpha,4abeta,10aalpha))-hylethyl)
[1theta-(1alpha,4abeta,10aalpha)]-hylethyl)
1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-,[1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine
13-isopropylpodocarpa-8,11,13-trien-15-amine
13-trien-15-amine,13-isopropyl-podocarpa-11
1-phenanthrenemethanamine,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-met
Dehydrobietylamine
DEHYDROABIETYLAMINE, TECH., 60%
DehydroabietylamineTech60%
1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)- | [EINECS(EC#)]
215-899-7 | [Molecular Formula]
C20H31N | [MDL Number]
MFCD00213430 | [Molecular Weight]
285.47 | [MOL File]
1446-61-3.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow viscous liquid | [Melting point ]
44.50℃ | [Boiling point ]
417.89°C (rough estimate) | [density ]
0.963±0.06 g/cm3 (20 ºC 760 Torr) | [refractive index ]
n20/D 1.546(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform, DMSO, Methanol | [form ]
White solid. | [pka]
10.13±0.29(Predicted) | [color ]
Pale Yellow | [optical activity]
[α]20/D +56.1°, c = 2.4 in pyridine | [Usage]
A primary amine with high molecular weight; shows a strong antibiotic effect with a broad spectrum of activity against Staphylococcus p.a. (sic), Escherichia coli, Mycobacterium tuberculosis, and Candida albicans. | [BRN ]
3084620 | [CAS DataBase Reference]
1446-61-3(CAS DataBase Reference) | [EPA Substance Registry System]
Dehydroabietylamine (1446-61-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
TP8701000
| [F ]
10-23 | [HS Code ]
29214990 | [Hazardous Substances Data]
1446-61-3(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow viscous liquid | [Uses]
Dehydroabiethylamine is a primary amine with high molecular weight; shows a strong antibiotic effect with a broad spectrum of activity against Staphylococcus p.a. (sic), Escherichia coli, Mycobacterium tuberculosis, and Candida albicans. | [Definition]
ChEBI: [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine is a diterpenoid. | [Biological Activity]
CB 1 agonist. Displaces binding of [ 3 H]-SR141716A with an IC 50 value of 2.86 μ M. | [storage]
Store at -20°C | [Purification Methods]
The crude base is purified by converting 2g of base in toluene (3.3mL) into the acetate salt by heating at 65-70o with 0.46g of AcOH, and the crystals are collected and dried (0.96g from two crops, m 141-143o). The acetate salt is dissolved in warm H2O, basified with aqueous NaOH and extracted with *C6H6. The dried extract (MgSO4) is evaporated in vacuum leaving a viscous oil which crystallises and can be distilled. [Gottstein & Cheney J Org Chem 30 2072 1965.] The picrate has m 234-236o (from aqueous MeOH), and the formate has m 147-148o (from heptane). [Beilstein 12 IV 3005.] |
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