| Identification | Back Directory | [Name]
ZM 241385 | [CAS]
139180-30-6 | [Synonyms]
CS-2353
ZM 241385
ZM 241385; ZM241385; ZM-241385
4-(2-[7-AMINO-2-(2-FURYL)[1,2,4]TRIAZOLO[2,3-A][1,3,5]TRIAZIN-5-YLAMINO]ETHYL)PHENO
4-(2-[7-AMINO-2-(2-FURYL)[1,2,4]TRIAZOLO[2,3-A][1,3,5]TRIAZIN-5-YLAMINO]ETHYL)PHENOL
4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol
Phenol, 4-[2-[[7-amino-2-(2-furanyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]- | [Molecular Formula]
C16H15N7O2 | [MDL Number]
MFCD01074804 | [MOL File]
139180-30-6.mol | [Molecular Weight]
337.34 |
| Chemical Properties | Back Directory | [density ]
1.59±0.1 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: >15mg/mL | [form ]
powder | [pka]
10.03±0.15(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
ZM 241385 is a selective and potent Adenosine A2A-R antagonist. | [Definition]
ChEBI: 4-[2-[[7-amino-2-(2-furanyl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]phenol is a diamino-1,3,5-triazine. | [Biochem/physiol Actions]
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders. | [storage]
Room temperature |
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