| Identification | Back Directory | [Name]
DECURSINOL ANGELATE | [CAS]
130848-06-5 | [Synonyms]
Acutilobin
Decursinol mebutate
DECURSINOL ANGELATE
2-Butenoic acid, 2-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (2Z)- | [Molecular Formula]
C19H20O5 | [MDL Number]
MFCD06796687 | [MOL File]
130848-06-5.mol | [Molecular Weight]
328.36 |
| Chemical Properties | Back Directory | [Melting point ]
93-94 °C | [Boiling point ]
469.4±45.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 2 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
Decursinol Angelate is a pyranocoumarin isolated from medical plant Angelica gigas th at exhibits potent anti-inflammatory properties. Decursinol Angelate appears to suppress type 17 helper T (Th17) cell responses in dextran sodium sulfate-induced colitis model. Decursinol Angelate reduces the production of NF-KB and COX-2 induced proinflammatory cytokine levels on TPA induced mice ear edema. |
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