| Identification | More | [Name]
Carboxyethylgermanium sesquioxide | [CAS]
12758-40-6 | [Synonyms]
3,3'-(1,3-DIOXO-1,3-DIGERMOXANEDIYL)BISPROPIONIC ACID
BETA-CARBOXYETHYLGERMANIUM OXIDE
BETA-CARBOXYETHYLGERMANIUM SESQUIOXIDE
BIS[2-CARBOXYETHYLGERMANIUM(IV)] SESQUIOXIDE
BIS(2-CARBOXYETHYLGERMANIUM SESQUIOXIDE)
BIS-BETA CARBOXYETHYLGERMANIUM SESQUIOXIDE
BIS(CARBOXYETHYLGERMANIUM SESQUIOXIDE)
CARBOXYETHYLGERMANIUM SESQUIOXIDE
GE 132
GERMANIUM SESQUIOXIDE
ORGANIC GERMANIUM
3,3-(1,3-dioxo-1,3-digermoxanediyl)-bispropionic
REPAGERMANIUM
99.7%
GERMANIUMSESQUIOXIDE,POWDER
proxigermanium
1-PHENYL-2-CARBOXYLETHYLGERMANIUMSESQUISULPHIDE
2-Carboxyethylgermanium sesquioxide
3,3'-(1,3-Dioxo-1,3-digermoxanediyl)dipropionic acid
Bis(carboxyethylgermanium) sesquioxide, 99.7% | [EINECS(EC#)]
235-800-0 | [Molecular Formula]
C6H10Ge2O7 | [MDL Number]
MFCD00049319 | [Molecular Weight]
339.42 | [MOL File]
12758-40-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
320°C | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Base (Sparingly) | [form ]
Solid | [pka]
3.6(at 25℃) | [color ]
White to Off-White | [Specific Gravity]
1.280 | [Odor]
wh. odorless powd. | [Water Solubility ]
Slightly soluble in water. | [Hydrolytic Sensitivity]
4: no reaction with water under neutral conditions | [Merck ]
7795 | [InChIKey]
XEABSBMNTNXEJM-UHFFFAOYSA-N | [CAS DataBase Reference]
12758-40-6(CAS DataBase Reference) | [EPA Substance Registry System]
12758-40-6(EPA Substance) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
2
| [RTECS ]
UA2459750
| [TSCA ]
Yes | [HS Code ]
2931.90.9051 | [Safety Profile]
Moderately toxic by
intravenous route. Experimental
reproductive effects. See also
GERMANIUM COMPOUNDS. | [Toxicity]
LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz) |
| Hazard Information | Back Directory | [Description]
Propagermanium, the first organogermanium compound marketed as a
pharmaceutical, is indicated for the oral treatment of chronic hepatitis B.
Propagermanium is reported to enhance production of interferon α/β in virus infected
mice and in human peripheral blood mononuclear cells but does not inhibit the growth
of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune
system against virus infection was proposed to be responsible for its antiviral
activity. Propagermanium also exhibits potent antitumor activity, reportedly via
stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y,
which induces the generation and activation of cytotoxic macrophages leading to
elimination of tumor cells. Propagermanium has been reported to regulate calcium
metabolism and to alleviate cancerous pain and osteocope. | [Originator]
Sanwa Kagaku (Japan) | [Uses]
antifungal and antiseptic | [Definition]
ChEBI: Propagermanium is an organogermanium compound. | [Brand name]
Serosion | [General Description]
Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics. |
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