| Identification | More | [Name]
SACLOFEN | [CAS]
125464-42-8 | [Synonyms]
3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID
BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID
BETA-(AMINOMETHYL)-4-CHLORO-BENZENEETHANESULPHONIC ACID
(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID
SACLOFEN
SACLOFEN SELECTIVE GABA(B) REC
β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid | [Molecular Formula]
C9H12ClNO3S | [MDL Number]
MFCD00216817 | [Molecular Weight]
249.71 | [MOL File]
125464-42-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
310-315℃ (decomposition) | [density ]
1.437±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
0.1 M NaOH: 20 mg/mL
| [form ]
solid
| [pka]
1.15±0.50(Predicted) | [color ]
white
| [Water Solubility ]
Soluble in water (10mM) | [InChIKey]
JYLNVJYYQQXNEK-UHFFFAOYSA-N | [CAS DataBase Reference]
125464-42-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats. | [Uses]
Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons | [Definition]
ChEBI: 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid is an organochlorine compound. | [Biological Activity]
Selective antagonist at GABA B receptors. | [Biochem/physiol Actions]
Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action. | [storage]
Store at -20°C |
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