Identification | More | [Name]
2'-DEOXY-2'-FLUOROTHYMIDINE | [CAS]
122799-38-6 | [Synonyms]
1-(2'-DEOXY-2'-FLUORO-BETA-D-RIBOFURANOSYL)-5-METHYLURACIL 2,4(1H,3H)-PYRIMIDINENONE, 1(2-DEOXY-2-FLUORO-BETA-D-RIBOFURANOSYL)-5-METHYL 2'-DEOXY-2'-FLUORO-5-METHYLURIDINE 2'-DEOXY-2'-FLUOROTHYMIDINE 5-METHYL-2'-FLUORO-D-URIDINE 5-METHYL-2'-FLUOROURACIL 2'-Fluoro-2'-deoxythymidine | [Molecular Formula]
C10H13FN2O5 | [MDL Number]
MFCD03788702 | [Molecular Weight]
260.22 | [MOL File]
122799-38-6.mol |
Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1]. | [References]
[1] Wiebe LI, et al. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Curr Radiopharm. 2012 Jan;5(1):38-46. DOI:10.2174/1874471011205010038 |
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