| Identification | Back Directory | [Name]
LY2811376 | [CAS]
1194044-20-6 | [Synonyms]
CS-1893
LY2811376
LY2811376, >=98%
LY2811376 USP/EP/BP
LY 2811376;LY-2811376
(4S)-4-(2,4-difluoro-5-pyriMidin-5-ylphenyl)-4-Methyl-5,6-dihydro-1,3-thiazin-2-aMine
(S)-4-(2,4-difluoro-5-(pyriMidin-5-yl)phenyl)-4-Methyl-5,6-dihydro-4H-1,3-thiazin-2-aMine
(4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-thiazin-2-amine
4H-1,3-Thiazin-2-amine, 4-[2,4-difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-, (4S)-
LY 2811376,(4S)-4-[2,4-Difluoro-5-(5-pyriMidinyl)phenyl]-5,6-dihydro-4-Methyl-4H-1,3-thiazin-2-aMine
N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl LY2811376 | [Molecular Formula]
C15H14F2N4S | [MDL Number]
MFCD18074525 | [MOL File]
1194044-20-6.mol | [Molecular Weight]
320.36 |
| Chemical Properties | Back Directory | [Boiling point ]
486.5±55.0 °C(Predicted) | [density ]
1.42 | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
crystalline solid | [pka]
5.60±0.40(Predicted) | [color ]
White to khaki |
| Hazard Information | Back Directory | [Uses]
LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression. | [storage]
Store at -20°C |
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