| Identification | More | [Name]
2,2'-Dithiosalicylic acid | [CAS]
119-80-2 | [Synonyms]
2-(2-CARBOXYPHENYL)DISULFANYLBENZOIC ACID
2,2'-DITHIOBENZOIC ACID
2,2-DITHIOBENZOIC ACID
2,2'-DITHIODIBENZOIC ACID
2,2-DITHIODIBENZOIC ACID
2,2'-DITHIOSALICYLIC ACID
2-CARBOXYPHENYL DISULFIDE
AKOS AUF01570
BIS(2-CARBOXYPHENYL) DISULFIDE
DIPHENYL DISULFIDE-2,2'-DICARBOXYLIC ACID
DITHIOSALICYLIC ACID
2,2’-dithiobis(benzoicacid)
2,2’-dithiobis-benzoicaci
2,2’-dithiodibenzoesaeure
2,2’-dithiodi-benzoicaci
bis(o-carboxyphenyl)disulfide
di(2-carboxyphenyl) disulphide
2,2'-Dithiosalicy acid
2,2'-DITHIOSALICYLIC ACID, TECH., 85%
2-Hydroxybenzenecarbothioic acid | [EINECS(EC#)]
204-352-8 | [Molecular Formula]
C14H10O4S2 | [MDL Number]
MFCD00002465 | [Molecular Weight]
306.36 | [MOL File]
119-80-2.mol |
| Chemical Properties | Back Directory | [Appearance]
brown powder | [Melting point ]
287-290 °C(lit.)
| [Boiling point ]
416.97°C (rough estimate) | [density ]
1.4555 (rough estimate) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.4950 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Powder | [pka]
3.02±0.36(Predicted) | [color ]
Brown | [Water Solubility ]
insoluble | [BRN ]
2221810 | [InChIKey]
LBEMXJWGHIEXRA-UHFFFAOYSA-N | [LogP]
1.61 at 25℃ and pH6.2-6.48 | [CAS DataBase Reference]
119-80-2(CAS DataBase Reference) | [EPA Substance Registry System]
119-80-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
DG9660000
| [Hazard Note ]
Harmful/irritant | [TSCA ]
Yes | [HS Code ]
29309070 | [Toxicity]
LD50 ipr-mus: 367 mg/kg ARZNAD 21,284,71 |
| Hazard Information | Back Directory | [Chemical Properties]
brown powder | [Uses]
2,2'-Dithiosalicylic acid is an organosulfur compound produced from dibenzothiophene metabolites that is in turn biodegraded into transient metabolites such as benzoic acid.It is used in the preparation of a new class of anti-HIV-1 agents.
| [General Description]
2,2′-Dithiodibenzoic acid is an sulfhydryl modifying reagent. 2,2′-Dithiodibenzoic acid on cocrystallization with imidazole or 4-methylimidazole affords bis(imidazolium) 2,2′-dithiodibenzoate and 4-methylimidazolium 2-[(2-carboxyphenyl)disulfanyl]benzoate organic salt, respectively. It also cocrystallizes with isonicotinohydrazide from methanol solution to afford the 1:2 cocrystal, 2,2′-dithiodibenzoic acid-isonicotinohydrazide. | [Safety Profile]
Poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofSOx. | [Synthesis]
A preparation method of 2,2'-dithiosalicylic acid is as follows: using anthranilic acid as raw material and performing a diazotization reaction with sodium nitrite and hydrochloric acid at 0 to 10°C to obtain a diazo liquid. The liquid reacts with liquid sulfur dioxide for 0.5 to 3 hours in the presence of a catalyst and a cocatalyst at -20~~-10°C and then is kept at 80~100°C for 0.5~2 hours, cooled, and filtered to obtain 2,2'-Dithiosalicylic acid.
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