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ChemicalBook--->CAS DataBase List--->1188-37-0

1188-37-0

1188-37-0 Structure

1188-37-0 Structure
IdentificationMore
[Name]

N-Acetyl-L-glutamic acid
[CAS]

1188-37-0
[Synonyms]

ACETYL-L-GLUTAMIC ACID
AC-GLU-OH
L-2-ACETAMIDOGLUTARIC ACID
N-ACETYL-L-GLU
N-ACETYL-L-GLUTAMIC ACID
N-AC-L-GLU
N-ALPHA-ACETYL-L-GLUTAMIC ACID
acetylglutamicacid
L-Glutamic acid, N-acetyl-
l-glutamicaci
l-n-acetylglutamicacid
n-acetylglutamate
n-acetylglutamic
N-Acetylglutamic acid
n-acetyl-glutamicaci
n-acetylglutamicacid
n-acetyl-l-glutamicaci
N-Acetyl-L-glutamate
N-Acetyl-L-Glutamic
N-Acetyl-L(DL)-Glutamic acid
[EINECS(EC#)]

214-708-4
[Molecular Formula]

C7H11NO5
[MDL Number]

MFCD00002802
[Molecular Weight]

189.17
[MOL File]

1188-37-0.mol
Chemical PropertiesBack Directory
[Appearance]

white crystalline powder
[Melting point ]

194-196 °C(lit.)
[alpha ]

-16 º (c=1, water)
[Boiling point ]

324.41°C (rough estimate)
[density ]

1.4119 (rough estimate)
[FEMA ]

4752 | N-ACETYL GLUTAMATE
[refractive index ]

-15 ° (C=1, H2O)
[storage temp. ]

0-6°C
[solubility ]

36g/l (Lit.)
[form ]

Solid
[pka]

3.45±0.10(Predicted)
[color ]

White
[optical activity]

[α]22/D 15.6°, c = 1 in H2O
[Water Solubility ]

2.7 g/100 mL (20 ºC)
[BRN ]

1727473
[LogP]

-2.131 (est)
[CAS DataBase Reference]

1188-37-0(CAS DataBase Reference)
[NIST Chemistry Reference]

N-acetyl-l-glutamic acid(1188-37-0)
[EPA Substance Registry System]

1188-37-0(EPA Substance)
Safety DataBack Directory
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

2
[RTECS ]

LZ9725000
[TSCA ]

Yes
[HS Code ]

29241900
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N-Acetyl-L-glutamic acid(1188-37-0).msds
Hazard InformationBack Directory
[Chemical Properties]

white crystalline powder
[Uses]

N-Acetyl-L-glutamic Acid is the N-Acetyl analogue of the non-essential amino acid, L-glutamic acid (G596960). N-Acetyl-L-glutamic Acid activates carbamoyl phosphate synthetase in the urea cycle.
[Uses]

N-Acetyl-L-glutamic acid is used as pharmaceutical intermediates.
[Uses]

Substrate for acetylglutamate kinase. Inhibitor of N-acetyl-L-glutamate synthetase
[Definition]

ChEBI: N-acetyl-L-glutamic acid is an N-acyl-L-amino acid that is L-glutamic acid in which one of the amine hydrogens is substituted by an acetyl group. It has a role as a Saccharomyces cerevisiae metabolite and a human metabolite. It is a N-acetyl-L-amino acid and a N-acyl-L-glutamic acid. It is functionally related to a L-glutamic acid. It is a conjugate acid of a N-acetyl-L-glutamate(1-).
[reaction suitability]

reaction type: solution phase peptide synthesis
[Purification Methods]

A likely impurity is glutamic acid. Crystallise it from boiling water. It inhibits N-acetyl-L-glutamate synthase. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1948 1961, Shigesada & Tatibana Eur J Biochem 84 285 1978, Coude Biochem Biophys Res Commun 102 1016 1981, Beilstein 4 IV 3047.]
Spectrum DetailBack Directory
[Spectrum Detail]

N-Acetyl-L-glutamic acid(1188-37-0)MS
N-Acetyl-L-glutamic acid(1188-37-0)1HNMR
N-Acetyl-L-glutamic acid(1188-37-0)13CNMR
N-Acetyl-L-glutamic acid(1188-37-0)IR1
N-Acetyl-L-glutamic acid(1188-37-0)IR2
N-Acetyl-L-glutamic acid(1188-37-0)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

N-Acetyl-L-glutamic acid, 99%(1188-37-0)
[Sigma Aldrich]

1188-37-0(sigmaaldrich)
[TCI AMERICA]

N-Acetyl-L-glutamic Acid,>98.0%(LC)(T)(1188-37-0)
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