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ChemicalBook--->CAS DataBase List--->118289-17-1

118289-17-1

118289-17-1 Structure

118289-17-1 Structure
IdentificationMore
[Name]

2-Bromo-4-pyridinecarboxaldehyde
[CAS]

118289-17-1
[Synonyms]

2-BROMO-4-FORMYLPYRIDINE
2-BROMO-4-PYRIDINECARBOXALDEHYDE
2-BROMOPYRIDINE-4-CARBALDEHYDE
2-BROMOPYRIDINE-4-CARBOXALDEHYDE
2-Bromoisonicotinaldehyde
2-bromo-4-pyridinecarboxaldehydecarboxaldehyde
2-Bromopyridine-4-carbaldehyde ,97%
[EINECS(EC#)]

624-388-1
[Molecular Formula]

C6H4BrNO
[MDL Number]

MFCD04039311
[Molecular Weight]

186.01
[MOL File]

118289-17-1.mol
Chemical PropertiesBack Directory
[Melting point ]

52-56°C
[Boiling point ]

272.9±20.0 °C(Predicted)
[density ]

1.683±0.06 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

soluble in Acetone
[form ]

Crystalline Powder
[pka]

-1.18±0.10(Predicted)
[color ]

Pale yellow
[Sensitive ]

Air Sensitive
[Detection Methods]

HPLC,NMR
[BRN ]

4243166
[CAS DataBase Reference]

118289-17-1(CAS DataBase Reference)
[Storage Precautions]

Store under nitrogen
Safety DataBack Directory
[Hazard Codes ]

Xi,Xn,F
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R10:Flammable.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HazardClass ]

IRRITANT
[HS Code ]

29333990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethyl acetate-->Sulfuric acid-->Tetrahydrofuran-->Sodium carbonate-->Benzene-->Sodium borohydride-->N-Bromosuccinimide-->Sodium thiosulfate-->Potassium dichromate-->Boron trifluoride diethyl etherate-->2-Bromo-4-methylpyridine
[Preparation Products]

2-(TRIFLUOROMETHYL)-PYRIDINE-4-CARBOXALDEHYDE-->2-(thiophen-3-yl)isonicotinaldehyde-->(2-Bromo-pyridin-4-ylmethyl)-isopropyl-amine-->Pyridine, 2-bromo-4-(dimethoxymethyl)-
Hazard InformationBack Directory
[Uses]

2-Bromo-4-pyridinecarboxaldehyde is a pharmaceutical intermediate ingredient used in the synthesis of Lafutidine, a histamine H2 receptor antagonist used in the treatment of gastrointestinal disorders such as gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.
Spectrum DetailBack Directory
[Spectrum Detail]

2-Bromo-4-pyridinecarboxaldehyde(118289-17-1)FT-IR
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

2-Bromopyridine-4-carboxaldehyde, 97%(118289-17-1)
[Sigma Aldrich]

118289-17-1(sigmaaldrich)
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