| Identification | More | [Name]
LUZINDOLE | [CAS]
117946-91-5 | [Synonyms]
N-0774
LUZINDOLE
Luzindole N
Luzindole Solution, 100ppm
N-ACETYL-2-BENZYLTRYPTAMINE
2-Benzyl-N-acetyltryptaMine
LuzindoleN-Acetyl-2-benzyltryptamine
N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide
n-[2-[2-(phenylmethyl)-1h-indol-3-yl]ethyl]acetamide
AcetaMide, N-[2-[2-(phenylMethyl)-1H-indol-3-yl]ethyl]-
N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide, N-Acetyl-2-benzyltryptamine | [Molecular Formula]
C19H20N2O | [MDL Number]
MFCD00672498 | [Molecular Weight]
292.37 | [MOL File]
117946-91-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Amorphous Solid | [Melting point ]
44-46°C | [Boiling point ]
434.31°C (rough estimate) | [density ]
1.1045 (rough estimate) | [refractive index ]
1.6140 (estimate) | [storage temp. ]
−20°C
| [solubility ]
DMSO: 5 mg/mL
| [form ]
White to off-white crystalline solid. | [pka]
16.36±0.46(Predicted) | [color ]
Off-White to Yellow | [Water Solubility ]
Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water. | [Usage]
A melatonin receptor antagonist | [Stability:]
Store at -20°C | [CAS DataBase Reference]
117946-91-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
AC7765700 | [HS Code ]
29339980 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Amorphous Solid | [Uses]
A melatonin receptor antagonist | [Uses]
Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response | [Definition]
ChEBI: A member of the class of indoles that is tryptamine in which one of the amino hydrogens is replaced by an acetyl group while the hydrogen at position 2 is replaced by a benzyl group. | [Biological Activity]
Melatonin antagonist. | [Biochem/physiol Actions]
Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype. | [storage]
Store at -20°C |
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