| Identification | More | [Name]
D-LUCIFERIN POTASSIUM SALT | [CAS]
115144-35-9 | [Synonyms]
4,5-DIHYDRO-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-4-THIAZOLECARBOXYLIC ACID POTASSIUM SALT
BEETLE LUCIFERIN, POTASSIUM SALT
D-(-)-2-[6'-HYDROXY-2'-BENZOTHIAZOLYL]DELTA-THIAZOLINE-4-CARBOXYLIC ACID POTASSIUM SALT
D-LUCIFERIN FIREFLY, POTASSIUM SALT
D-LUCIFERIN, MONOPOTASSIUM SALT
D-LUCIFERIN POTASSIUM SALT
D-LUCIFERIN SYNTHETIC POTASSIUM SALT
D-Luciferenpotassiumsalt
(S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylicacid,potassiumsalt
(D)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid, Firefly, potassium salt
D-Luciferin*K
D-LUCIFERINPOTASSIUMSALT,99% | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C11H7KN2O3S2 | [MDL Number]
MFCD00044928 | [Molecular Weight]
318.41 | [MOL File]
115144-35-9.mol |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMF:16.7(Max Conc. mg/mL);52.45(Max Conc. mM)
DMSO:7.5(Max Conc. mg/mL);23.55(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.79(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);0.31(Max Conc. mM)
Water:32.0(Max Conc. mg/mL);100.5(Max Conc. mM) | [form ]
A crystalline solid | [color ]
Light yellow | [BRN ]
5416262 | [InChI]
InChI=1/C11H8N2O3S2.K.H/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;;/h1-3,7,14H,4H2,(H,15,16);;/t7-;;/s3 | [InChIKey]
UMBKGTQQGYPQBE-OGFXRTJISA-M | [SMILES]
C([C@H]1CSC(C2=NC3C=CC(O)=CC=3S2)=N1)(=O)O.[KH] |&1:1,r| | [CAS DataBase Reference]
115144-35-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
D-Luciferin potassium salt(115144-35-9) is a water soluble form of D-Luciferin. D-Luciferin is a common bioluminescent substrate used for imaging of firefly luciferase expression with peak chemiluminescent emission at 560 nm. The ATP dependant luciferin oxidation is catalyzed by the Luciferase enzyme encoded by luc gene.
| [Chemical Properties]
Yellow powder | [Uses]
D-Luciferin Potassium Salt is a class of light-emitting heterocyclic compounds found in organisms that cause bioluminescence, such as firefly. This compound creates light through the process of oxidative decarboxylation by luciferase while ATP is present. In cell culture, D-Luciferin Potassium Salt is used to achieve highly sensitive bioluminescence detection. Recently, Luciferin was used to measure the uptake of mRNA in preparation of the vaccine against COVID-19. | [Application]
D-Luciferin may be used as a substrate in luciferase-based (EC 1.13.12.7) bioluminescence imaging and cell-based high-throughput screening applications. ATP can be measured with a reagent made up of D-luciferin and luciferase from firefly. D-Luciferin may be used and studied as a partial agonist for G protein-coupled receptor-35 (GPR35). Used for imaging the expression of the LUC marker gene and luciferase-fusion conjugates in living cells, tissues and organisms. Extensively utilized in reporter gene assays, immunoassays and hygiene monitoring. |
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