| Identification | More | [Name]
2-Bromofluorene | [CAS]
1133-80-8 | [Synonyms]
2-bromo-9h-fluorene
2-BROMOFLUORENE
2-Bromofluorene, Pract.
2-Bromofluorene, Tech. | [EINECS(EC#)]
214-480-6 | [Molecular Formula]
C13H9Br | [MDL Number]
MFCD00001115 | [Molecular Weight]
245.11 | [MOL File]
1133-80-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to slightly yellow crystalline powder | [Melting point ]
112-114 °C (lit.) | [Boiling point ]
185 °C/135 mmHg (lit.) | [density ]
1.4187 (rough estimate) | [refractive index ]
1.6290 (estimate) | [Fp ]
185°C/135mm | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in chloroform and ethyl acetate. | [form ]
Slightly Crystalline Powder or Flakes | [color ]
White to slightly yellow | [BRN ]
1946701 | [InChIKey]
FXSCJZNMWILAJO-UHFFFAOYSA-N | [CAS DataBase Reference]
1133-80-8(CAS DataBase Reference) | [NIST Chemistry Reference]
9H-Fluorene, 2-bromo-(1133-80-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29039900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly yellow crystalline powder | [Synthesis Reference(s)]
Journal of the American Chemical Society, 80, p. 4327, 1958 DOI: 10.1021/ja01549a053 | [General Description]
2-Bromofluorene is a nonintrusive end-capping reagent to control molecular weights and to generate well-defined oligomers. |
| Questions And Answer | Back Directory | [description]
2-Bromofluorene is an isolated product of coal tar and its derivatives are used as important raw materials for fine chemicals. It is often used as synthetic intermediate of the OLED material in industry, by the reaction of barbier-type ultrasonic radiation, It is also used to study the conversion of aryl bromides to aryl triethoxy silane.
Lab Preparation Methods: propylene carbonate is used as solvent, N-bromosuccinimide (NBS) is used as brominated reagent to carry bromination reaction of fluorine, and this reaction can synthesize 2-bromofluorene and 2,7-dibromofluorene. By the investigation of reaction temperature, NBS amount, the adding methods, the optimal reaction conditions for the synthesis of 2-bromofluorene is confirmed. The optimal reaction conditions are: reaction temperature is 23℃, the molar ratio of NBS with fluorine is 1.1:1, NBS is added by stage addition. First fluorene and propylene carbonate is preheated to 60℃, so fluorine is all dissolved, and then it drops to the reaction temperature, NBS is added by stage addition. 2-bromofluorene and 2,7-dibromofluorene recrystallizes with ethanol and acetic acid respectively, the purity of target product of liquid chromatography can reach more than 99%. | [Uses]
(1) It can be used as pharmaceutical intermediate, it is also important intermediate in the synthesis of optoelectronic material.
(2) By ultrasonic radiation of Barbier-type reaction, 2-bromofluorene is used for the study of aryl bromide (aryl bromides) converts to aryl triethoxysilane (aryltriethoxysilanes). It is also for the preparation of N-carbazole fluorene oligomers end-capped. It can be used as intermediates of OLED materials in industry. |
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