Identification | More | [Name]
L-4-Fluorophenylalanine | [CAS]
1132-68-9 | [Synonyms]
3-(4-FLUOROPHENYL)-L-ALANINE 4-FLUORO-L-PHENYLALANINE 4-FLUORO-PHENYLALANINE 4-FLUORO-PHE-OH H-L-PHE(4-F)-OH H-P-FLUORO-PHE-OH H-PHE(4-F)-OH H-PHE(P-F)-OH L-3-(4-Fluorophenyl)alanine L-4-FLUOROPHE L-4-FLUOROPHENYLALANINE P-FLUORO-L-PHENYLALANINE P-FLUORO-PHENYLALANINE RARECHEM BK PT 0031 (S)-2-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID (S)-2-Amino-3-(4'-Fluorophenyl)Propanoic Acid 4-Fluoro-L-Phenylalanine HCl (2R)-2-amino-3-(4-fluorophenyl)propanoic acid H-p-Fluoro-Phe-OH (4-Fluoro-L-Phenylalanine) L-4-F-Phe-OH | [EINECS(EC#)]
145-896-5 | [Molecular Formula]
C9H10FNO2 | [MDL Number]
MFCD00063064 | [Molecular Weight]
183.18 | [MOL File]
1132-68-9.mol |
Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
~255 °C (dec.) | [alpha ]
-26.5 º (c=1, H2O 25 ºC) | [Boiling point ]
313.3±32.0 °C(Predicted) | [density ]
1.1939 (estimate) | [storage temp. ]
Store at RT. | [pka]
2.20±0.10(Predicted) | [Water Solubility ]
Soluble in water and 0.5M HCl (50 mg/ml). | [BRN ]
2416148 | [CAS DataBase Reference]
1132-68-9(CAS DataBase Reference) |
Safety Data | Back Directory | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
DW1765000 | [Hazard Note ]
Harmful | [HS Code ]
29224999 |
Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Uses]
4-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that has been used to study the regulation of that enzyme. | [Definition]
ChEBI: A L-phenylalanine derivative that is L-phenylalanine in which the hydrogen at position 4 on the benzene ring is replaced by a fluoro group. | [Purification Methods]
It is recrystallised from aqueous EtOH. The (R)-N-acetyl derivative has m 142-145o, [] D -38.6o (c 8, EtOH). [Bennett & Nieman J Am Chem Soc 72 1800 1950, Beilstein 14 III 1268.] |
|
|